Keywords: Mosquito control

Aedes aegypti Controls Ae. aegypti: SIT and IIT—An Overview

Robert L. Aldridge; Seth Gibson; Kenneth J. Linthicum,  Journal of the American Mosquito Control Association,  20:32-49. 2024.
The sterile insect technique (SIT) and the incompatible insect technique (IIT) are emerging and potentially revolutionary tools for controlling Aedes aegypti (L.), a prominent worldwide mosquito vector threat to humans that is notoriously difficult to reduce or eliminate in ...
Keywords: , , , , , , , , , , ,

Advances and challenges in synthetic biology for mosquito control

Shih-Che Weng, Reem A. Masri, Omar S. Akbari,  Trends in Parasitology,  2023.
Mosquito-borne illnesses represent a significant global health peril, resulting in approximately one million fatalities annually. West Nile, dengue, Zika, and malaria are continuously expanding their global reach, driven by factors that escalate mosquito populations and pathogen ...
Keywords: , , , , , , , , , , ,

Sterile Insect Technique (SIT) against Aedes Species Mosquitoes: A Roadmap and Good Practice Framework for Designing, Implementing and Evaluating Pilot Field Trials

C. F. Oliva, M. Q. Benedict, C. M. Collins, T. Baldet, R. Bellini, H. Bossin, J. Bouyer, V. Corbel, L. Facchinelli, F. Fouque, M. Geier, A. Michaelakis, D. Roiz, F. Simard, C. Tur and L.-C. Gouagna,  Insects,  12. 2021.
We offer here a pragmatic and accessible ‘roadmap’ for the pre-pilot and pilot phases to guide any interested party. This will support stakeholders, non-specialist scientists, implementers, and decision-makers. Applying these concepts will ensure, given adequate resources, a ...
Keywords: , , , , , , , , , , ,

Modeling the mutation and reversal of engineered underdominance gene drives

Edgington, MPA, Luke S.,  Journal of Theoretical Biology,  479:14-21. 2019.
A range of gene drive systems have been proposed that are predicted to increase their frequency and that of associated desirable genetic material even if they confer a fitness cost on individuals carrying them. Engineered underdominance (UD) is such a system and, in one version, ...
Keywords: , , , , , , , , , , ,

Ecological effects on underdominance threshold drives for vector control

D. Khamis, C. El Mouden, K. Kura and M. B. Bonsall,  Journal of Theoretical Biology,  456:1-15. 2018.
Here, ecological and epidemiological dynamics are coupled to a model of mosquito genetics to investigate theoretically the impact of different types of underdominance gene drive on disease prevalence. We model systems with two engineered alleles carried either on the same pair ...
Keywords: , , , , , , , , , , ,