Keywords: natural-populations
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A Protamine Knockdown Mimics the Function of Sd in Drosophila melanogasterL. F. Gingell and J. R. McLean, G3-Genes Genomes Genetics, 10:2111-2115. 2020.
Segregation Distorter (SD) is an autosomal meiotic drive system found worldwide in natural populations of Drosophila melanogaster. This gene complex induces the preferential and nearly exclusive transmission of the SD chromosome in SD/SD+ males. This selfish propagation occurs ... |
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Gene drives do not always increase in frequency: from genetic models to risk assessmentde Jong, TJ, Journal Fur Verbraucherschutz Und Lebensmittelsicherheit-Journal of Consumer Protection and Food Safety, 12:299-307. 2017.
Homing genes encode endonucleases that make a double stranded break in the DNA, destroying a target site on the homologous chromosome. When the cell repairs the break the homing allele is copied, converting a heterozygote into a homozygote. This results in gene drive (GD), an ... |
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Sperm competition suppresses gene drive among experimentally evolving populations of house miceManser, AL, A. K.; Simmons, L. W.; Firman, R. C., Molecular Ecology, 26:5784-5792. 2017.
Drive genes are genetic elements that manipulate the 50% ratio of Mendelian inheritance in their own favour, allowing them to rapidly propagate through populations. The action of drive genes is often hidden, making detection and identification inherently difficult. Yet drive ... |
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Wolbachia and cytoplasmic incompatibility in mosquitoesSinkins, SP, Insect Biochemistry and Molecular Biology, 34:723-729. 2004.
Wolbachia are maternally inherited bacteria that induce cytoplasmic incompatibility in mosquitoes, and are able to use these patterns of sterility to spread themselves through populations. For this reason they have been proposed as a gene drive system for mosquito genetic ... |
