MGDrivE: A modular simulation framework for the spread of gene drives through spatially-explicit mosquito populationsSánchez C, HMW, Sean L.; Bennett, Jared B.; Marshall, John M., Methods in Ecology and Evolution, 10:1-24. 2019.
Malaria, dengue, Zika, and other mosquito-borne diseases continue to pose a major global health burden through much of the world, despite the widespread distribution of insecticide-based tools and antimalarial drugs. The advent of CRISPR/Cas9-based gene editing and its ...
Keywords: Aedes aegypti, Anopheles gambiae, Gene drive, gene drive models, gene drive synthetic, inheritance pattern, insecticide resistance, landscape, life history, Mathematical model, mosquito, network, population dynamics, R package, synthetic homing drive
Foundation for the
National Institutes of Health