
Keywords: Nix
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Partial masculinization of Aedes aegypti females by conditional expression of NixB. B. Kojin, E. Jakes, J. K. Biedler, Z. Tu and Z. N. Adelman, PLOS Neglected Tropical Diseases, 16:e0010598. 2022.![]() Here, we report on the conditional expression of Nixin transgenic A. aegypti under the control of the tetracycline-dependent (Tet-off) system, with the goal of establishing repressible sex distortion. A masculinization phenotype was observed in three of the seven transgenic lines ... Keywords: Aedes, albopictus, genetic biocontrol, genetic sexing, mosquitoes, Nix, sex determination, SIT, sterile insect technique |
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Transgenic expression of Nix converts genetic females into males and allows automated sex sorting in Aedes albopictusC. Lutrat, R. P. Olmo, T. Baldet, J. Bouyer and E. Marois, bioRxiv, 2021.07.28.454191. 2021.![]() Aedes albopictus is a major vector of arboviruses. Better understanding of its sex determination is crucial for developing mosquito control tools, especially genetic sexing strains. In Aedes aegypti, Nix is the primary gene responsible for masculinization and Nix-expressing ... Keywords: Aedes, albopictus, genetic biocontrol, genetic sexing, mosquitoes, Nix, sex determination, SIT, sterile insect technique |

Contact
David O’Brochta
Foundation for the
National Institutes of Health
geneconvenevi@fnih.org
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