Keywords: P elements

Can transposable elements be used to drive disease refractoriness genes into vector populations?

M. G. Kidwell and J. M. C. Ribeiro,  Parasitology Today,  8:325-329. 1992.
A number of biological procedures are currently being considered as alternatives to insecticide-based methods for the control of insect vectors of disease. Among these are the adaptation of various genetic mechanisms to drive genes of interest, such as refractoriness to malaria ...
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Rapid spread of transposable P elements in experimental populations of Drosophila melanogaster.

A. G. Good, G. A. Meister, H. W. Brock, T. A. Grigliatti and D. A. Hickey,  Genetics,  1223:387-396. 1989.
The invasion of P elements in natural populations of Drosophila melanogaster was modeled by establishing laboratory populations with 1 %, 5% and 10% P genomes and monitoring the populations for 20 generations. In one experiment, the ability of flies to either induce or suppress ...
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Genetic-transformation of Drosophila with transposable element vectors

G. M. Rubin and A. C. Spradling,  Science,  218:348-353. 1982.
Exogenous DNA sequences were introduced into the Drosophila germ line. A rosy transposon (ry1), constructed by inserting a chromosomal DNA fragment containing the wild-type rosy gene into a P transposable element, transformed germ line cells in 20 to 50 percent of the injected ...
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