Keywords: pathogen blocking

Wolbachia wPip Blocks Zika Virus Transovarial Transmission in Aedes albopictus

Y. Guo, J. Guo, Y. Li, X. Zheng and Y. Wu,  Microbiol Spectrum,  e0263321. 2022.
Area-wide application of Wolbachia to suppress mosquito populations and their transmitted viruses has achieved success in multiple countries. However, the mass release of Wolbachia-infected male mosquitoes involves a potential risk of accidentally releasing fertile females. In ...
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Developing Wolbachia-based disease interventions for an extreme environment

P. A. Ross, S. Elfekih, S. Collier, M. J. Klein, S. S. Lee, M. Dunn, S. Jackson, Y. Zhang, J. K. Axford, X. Gu, M. S. Nasar, P. N. Paradkar, E. A. Taoufik, F. M. Jiggins, A. M. Almalik, M. B. Al-Fageeh and A. A. Hoffmann,  bioRxiv,  2022.07.26.501527. 2022.
Aedes aegypti mosquitoes carrying self-spreading, virus-blocking Wolbachia bacteria are being deployed to suppress dengue transmission. However, there are challenges in applying this technology in extreme environments. We introduced two Wolbachia strains into Ae. aegypti from ...
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Attempts to use breeding approaches in Aedes aegypti to create lines with distinct and stable relative Wolbachia densities

A. J. Mejia, L. Jimenez, H. L. C. Dutra, R. Perera and E. A. McGraw,  Heredity,  2022.
Wolbachia is an insect endosymbiont being used for biological control in the mosquito Aedes aegypti because it causes cytoplasmic incompatibility (CI) and limits viral replication of dengue, chikungunya, and Zika viruses. While the genetic mechanism of pathogen blocking (PB) is ...
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