Keywords: Pest eradication
Synthetic gene drives offer a novel solution for the control of invasive alien species. CRISPR-based gene drives can positively bias their own inheritance, and comprise a DNA sequence that is replicated by homologous recombination. Since gene drives can be positioned to silence ...
Keywords: CRISPR, Eradication, Evolution, extinction, Gene drive, gene drive synthetic, genetic biocontrol, house mice, invasive, manipulate, maternal nutrition, Mating system, models, Pest eradication, Population modelling, resistance, sex-ratio, species, Synthetic biology, Trojan-Y Chromosome, wild