Keywords: Plutella xylostella

Development of CRISPR/Cas9-Mediated Gene-Drive Construct Targeting the Phenotypic Gene in Plutella xylostella

M. Asad, D. Liu, J. Li, J. Chen and G. Yang,  Frontiers in Physiology,  13:938621. 2022.
The gene-drive system can ensure that desirable traits are transmitted to the progeny more than the normal Mendelian segregation. The clustered regularly interspersed palindromic repeats (CRISPR)/CRISPR-associated protein 9 (Cas9) mediated gene-drive system has been demonstrated ...
Keywords: , , , , , , , , ,

Towards CRISPR/Cas9-based gene drive in the diamondback moth Plutella xylostella

X. Xu, T. Harvey-Samuel, H. Siddiqui, J. Ang, M. A. E. Anderson, C. Reitmayer, E. Lovett, P. T. Leftwich, M. You and L. Alphey,  bioRxiv,  2021.10.05.462963. 2021.
Promising to provide powerful genetic control tools, gene drives have been constructed in multiple dipterans, yeast and mice, for the purposes of population elimination or modification. However, it remains unclear whether these techniques can be applied to lepidopterans. Here, we ...
Keywords: , , , , , , , , ,

CRISPR/Cas9-based functional characterization of the pigmentation gene ebony in Plutella xylostella

X. Xu, T. Harvey-Samuel, J. Yang, M. You and L. Alphey,  Insect Molecular Biology,  2021.
Abstract Body pigmentation is an important character of insects in adapting to biotic and abiotic environmental challenges. Additionally, based on the relative ease of screening, several genes involved in insect melanisation have been used in classic genetic studies or as visual ...
Keywords: , , , , , , , , ,

Genetically engineered moths may save kale chips

C. Poku,  BIOtechNOW,  2020.
Sea salt kale chips, bacon brussels sprouts, and buffalo cauliflower wings are under threat. Environmental activists will have you believe the biggest threat to our food system is pesticides. That’s not true, in fact, it’s insects—the very reason most pesticides are ...
Keywords: , , , , , , , , ,

Genetically engineered moths have been released into the wild to wipe out pests

K. Rogers,  CNN,  2020.
Genetically modified diamondback moths designed to wipe out wild pest populations were released in fields for the first time in New York state. Diamondback moths are migratory pests found in the Americas, Europe, New Zealand and Southeast Asia, but especially in areas where ...
Keywords: , , , , , , , , ,

GMO diamondback moth shows promise as sustainable pest control tool in first ever open-field release

Cornell University,  Genetic Literacy Project,  2020.
A newly published study reports a successful, first-ever open-field release of a self-limiting, genetically engineered diamondback moth, stating that it paves the way for an effective and sustainable approach to pest control. The diamondback moth, also known as Plutella ...
Keywords: , , , , , , , , ,

Male moths genetically modified to kill females released in the wild

M. Le Page,  New Scientist,  2020.
Genetically modified male diamondback moths designed to wipe out pest populations have been released in New York state. The field trial shows that these GM moths, whose female offspring die soon after hatching, could help control this major crop pest. Oxitec, the British ...
Keywords: , , , , , , , , ,

First Field Release of a Genetically Engineered, Self-Limiting Agricultural Pest Insect: Evaluating Its Potential for Future Crop Protection

A. M. Shelton, S. J. Long, A. S. Walker, M. Bolton, H. L. Collins, L. Revuelta, L. M. Johnson and N. I. Morrison,  Frontiers in Bioengineering and Biotechnology,  7:1-15. 2020.
Alternative, biologically-based approaches for pest management are sorely needed and one approach is to use genetically engineered insects. Herein we describe a series of integrated field, laboratory and modeling studies with the diamondback moth, Plutella xylostella, a serious ...
Keywords: , , , , , , , , ,

Identification and characterisation of a Masculinizer homolog in the diamondback moth Plutella xylostella

Harvey-Samuel, T., V. C. Norman, R. Carter, E. Lovett and L. Alphey,  Insect Molecular Biology,  2019:2019. 2019.
Recently, a novel sex-determination system was identified in the silkworm (Bombyx mori) in which a piRNA encoded on the female-specific W chromosome silences a Z-linked gene (Masculinizer) which would otherwise initiate male sex-determination and dosage compensation. ...
Keywords: , , , , , , , , ,