
Keywords: population eradication
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Genetic pest management technologies to control invasive rodentsD. Kanavy and D. Threadgill, Island invasives: scaling up to meet the challenge, 2019.![]() Many strategies exist to manage invasive pests on islands, ranging from poison to trapping, with varying degrees of success. Genetic technologies are increasingly being applied to insect pests, but so far, not to vertebrates. We are implementing a genetic strategy to eradicate ... Keywords: cre recombinase, DNA, drosophila-melanogaster, endonuclease genes, Evolution, gene drive evolution, gene drive models, gene drive natural, gene drive synthetic, history 2000-present, Homing, homing endonuclease, homologous recombination, horizontal transfer, intron, mechanisms, population eradication, population genetic engineering, protein, vector-borne diseases |
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Trialling gene drives to control invasive species: what, where and how?T. Harvey-Samuel, K. J. Campbell, M. Edgington and L. Alphey, Island invasives: scaling up to meet the challenge, 2019.![]() The control of invasive species would be enhanced through the addition of novel, more effective and sustainable pest management methods. One control option yet to be trialled in the field is to deploy transgene-based ‘Gene Drives’: technologies which force the inheritance of ... Keywords: cre recombinase, DNA, drosophila-melanogaster, endonuclease genes, Evolution, gene drive evolution, gene drive models, gene drive natural, gene drive synthetic, history 2000-present, Homing, homing endonuclease, homologous recombination, horizontal transfer, intron, mechanisms, population eradication, population genetic engineering, protein, vector-borne diseases |
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Site-specific selfish genes as tools for the control and genetic engineering of natural populationsBurt, A, Proceedings of the Royal Society B-Biological Sciences, 270:921-928. 2003.![]() Site-specific selfish genes exploit host functions to copy themselves into a defined target DNA sequence, and include homing endonuclease genes, group II introns and some LINE-like transposable elements. If such genes can be engineered to target new host sequences, then they can ... Keywords: cre recombinase, DNA, drosophila-melanogaster, endonuclease genes, Evolution, gene drive evolution, gene drive models, gene drive natural, gene drive synthetic, history 2000-present, Homing, homing endonuclease, homologous recombination, horizontal transfer, intron, mechanisms, population eradication, population genetic engineering, protein, vector-borne diseases |

Contact
David O’Brochta
Foundation for the
National Institutes of Health
geneconvenevi@fnih.org
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