
Keywords: protein
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Site-specific selfish genes as tools for the control and genetic engineering of natural populationsBurt, A, Proceedings of the Royal Society B-Biological Sciences, 270:921-928. 2003.![]() Site-specific selfish genes exploit host functions to copy themselves into a defined target DNA sequence, and include homing endonuclease genes, group II introns and some LINE-like transposable elements. If such genes can be engineered to target new host sequences, then they can ... Keywords: elements, gene drive evolution, gene drive genetics, gene drive natural, group-i introns, history, homing endonucleases, plants, protein, recombination, ribosomal-rna gene, saccharomyces-cerevisiae, sensu-stricto complex, sequences, site |
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Recurrent invasion and extinction of a selfish geneGoddard, MRB, A., Proceedings of the National Academy of Sciences of the United States of America, 96:13880-13885. 1999.![]() Homing endonuclease genes show super-Mendelian inheritance, which allows them to spread in populations even when they are of no benefit to the host organism. To test the idea that regular horizontal transmission is necessary for the long-term persistence of these genes, we ... Keywords: elements, gene drive evolution, gene drive genetics, gene drive natural, group-i introns, history, homing endonucleases, plants, protein, recombination, ribosomal-rna gene, saccharomyces-cerevisiae, sensu-stricto complex, sequences, site |

Contact
David O’Brochta
Foundation for the
National Institutes of Health
geneconvenevi@fnih.org
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