Keywords: protein

Site-specific selfish genes as tools for the control and genetic engineering of natural populations

Burt, A,  Proceedings of the Royal Society B-Biological Sciences,  270:921-928. 2003.
Site-specific selfish genes exploit host functions to copy themselves into a defined target DNA sequence, and include homing endonuclease genes, group II introns and some LINE-like transposable elements. If such genes can be engineered to target new host sequences, then they can ...
Keywords: , , , , , , , , , , , , , ,

Recurrent invasion and extinction of a selfish gene

Goddard, MRB, A.,  Proceedings of the National Academy of Sciences of the United States of America,  96:13880-13885. 1999.
Homing endonuclease genes show super-Mendelian inheritance, which allows them to spread in populations even when they are of no benefit to the host organism. To test the idea that regular horizontal transmission is necessary for the long-term persistence of these genes, we ...
Keywords: , , , , , , , , , , , , , ,