Variability in the durability of CRISPR-Cas immunityChabas, HN, A.; Meaden, S.; Westra, E. R.; Tremblay, D. M.; Pradier, L.; Lion, S.; Moineau, S.; Gandon, S., Philosophical Transactions of the Royal Society B-Biological Sciences, 374:1-9. 2019.
The durability of host resistance is challenged by the ability of pathogens to escape the defence of their hosts. Understanding the variability in the durability of host resistance is of paramount importance for designing more effective control strategies against infectious ...
Keywords: bias, clustered regularly, diversity, durability of resistance, durable resistance, Evolution, gene drive genetics, gene drive synthetic, interspaced short palindromic repeats-Cas, mutation rates, pathogen evolution, rates, virus
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