Keywords: resistance alleles

A homing rescue gene drive with multiplexed gRNAs reaches high frequency in cage populations but generates functional resistance

Hou S, Chen J, Feng R, Xu X, Liang N, Champer J.,  Journal of Genetics and Genomics,  2024.
CRISPR homing gene drive is a potent technology with considerable potential for managing populations of medically and agriculturally significant insects. It induces a bias in the inheritance of the drive allele in progeny, rapidly spreading the desired gene construct throughout ...
Keywords: , , , , ,