Keywords: RIDL

Oxitec Advances Process to Bring Friendly™ Mosquito Technology to California to Help Government Agencies Protect Public Health

Oxitec,  Oxitec,  2021.
Following successful launch of its Friendly™ Aedes aegypti pilot program in the Florida Keys, Oxitec, the leading developer of biological solutions to control pests that transmit disease, destroy crops and harm livestock, has requested approval from the U.S. Environmental ...
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Engineered expression of the invertebrate-specific scorpion toxin AaHIT reduces adult longevity and female fecundity in the diamondback moth Plutella xylostella

T. Harvey-Samuel, X. Xu, E. Lovett, T. Dafa'alla, A. Walker, V. C. Norman, R. Carter, J. Teal, L. Akilan, P. T. Leftwich, C. M. Reitmayer, H. A. Siddiqui and L. Alphey,  Pest Management Science,  2021.
To increase the flexibility of future genetic pest management systems in the diamondback moth, we aimed to assess the use of a non-cell-autonomous, invertebrate-specific, neurotoxic effector ? the scorpion toxin AaHIT. This AaHIT effector was designed to be secreted by ...
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EPA Approves Genetically Modified Mosquito Trial For Florida Keys

Nancy Klingener,  WLRN,  2020.
A plan to test genetically modified mosquitoes in the Florida Keys has received approval from the federal government.
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EPA Grants First Permit to Test Genetically Modified Mosquitoes

Adam Allington,  Bloomberg Law,  2020.
British biotech company Oxitec Ltd was granted an experimental use permit to release a genetically engineered type of the mosquito species Aedes aegypti, which is a known vector of Zika virus and viruses that cause yellow fever and dengue fever, the Environmental Protection ...
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EPA Approves Experimental Use Permit to Test Innovative Biopesticide Tool to Better Protect Public Health

EPA,  EPA,  2020.
Today, after extensive evaluation of the best available science and public input, the U.S. Environmental Protection Agency (EPA) has granted an experimental use permit (EUP) to Oxitec Ltd. to field test the use of genetically engineered Aedes aegypti mosquitoes as a way to reduce ...
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Genetic Control of Mosquitoes

Alphey, L.,  Annual Review of Entomology,  59:205-224. 2019.
Genetics can potentially provide new, species-specific, environmentally friendly methods for mosquito control. Genetic control strategies aim either to suppress target populations or to introduce a harm-reducing novel trait. Different approaches differ considerably in their ...
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A secret weapon against Zika and other mosquito-borne diseases

Nina Federoff,  TEDxMidAtlantic,  2017.
Where did Zika come from, and what can we do about it? Molecular biologist Nina Fedoroff takes us around the world to understand Zika's origins and how it spread, proposing a controversial way to stop the virus -- and other deadly diseases -- by preventing infected mosquitoes ...
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SCIENTIFIC OPINION: In response to the referral of 12 October 2015 concerning use of genetically modified mosquitoes for vector control

High Council for Biotechnology,  High Council for Biotechnology (France),  2017.
The Scientific Committee’s opinion describes emerging vector control techniques using GM mosquitoes, the current state of research into and development of these techniques and the outcomes of initial experiments worldwide. To date, only one technique has been developed to an ...
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Concept and history of genetic control

Scott, M. J. and Benedict, M. Q.,  Genetic Control of Malaria and Dengue,  2:31-54. 2016.
Genetic control of insects is an established method, mainly for insects that are important crop and veterinary pests such as medflies and screwworm. Efforts to use the same technologies against insects of medical importance, especially mosquitoes, have had limited success. The ...
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Genetic Control of Mosquitoes.

Alphey, L.,  Annual Review of Entomology,  59:205-224. 2014.
Genetics can potentially provide new, species-specific, environmentally friendly methods for mosquito control. Genetic control strategies aim either to suppress target populations or to introduce a harm-reducing novel trait. Different approaches differ considerably in their ...
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Field performance of engineered male mosquitoes

A. F. Harris, D. Nimmo, A. R. McKemey, N. Kelly, S. Scaife, C. A. Donnelly, C. Beech, W. D. Petrie and L. Alphey,  Nature Biotechnology,  29:1034-1037. 2011.
Mass-release of sterile male mosquitoes is a promising option for controlling dengue and malaria, but it has never been shown that lab-raised transgenic males can compete effectively with their wild counterparts outside laboratory conditions. Promising results from a restricted ...
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Field performance of engineered male mosquitoes

A. F. Harris, D. Nimmo, A. R. McKemey, N. Kelly, S. Scaife, C. A. Donnelly, C. Beech, W. D. Petrie and L. Alphey,  Nature Biotechnology,  29:1034-1037. 2011.
Mass-release of sterile male mosquitoes is a promising option for controlling dengue and malaria, but it has never been shown that lab-raised transgenic males can compete effectively with their wild counterparts outside laboratory conditions. Promising results from a restricted ...
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