Keywords: risk analysis

Procedurally Robust Risk Assessment Framework for Novel Genetically Engineered Organisms and Gene Drives

Kuzma, J.,  Regulation and Governance,  15:1144-1165. 2021.
In this article, a new framework for improving risk assessments of novel genetically engineered organisms (GEOs) is developed and applied. The Procedurally Robust Risk Assessment Framework (PRRAF) provides a set of principles and criteria for assessing and enhancing risk ...
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Gene drive strategies of pest control in agricultural systems: challenges and opportunities

M. Legros, J. M. Marshall, S. Macfadyen, K. R. Hayes, A. Sheppard and L. G. Barrett,  Evolutionary Applications,  2021.
Abstract Recent advances in gene editing technologies have opened new avenues for genetic pest control strategies, in particular around the use of gene drives to suppress or modify pest populations. Significant uncertainty, however, surrounds the applicability of these strategies ...
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Risk management recommendations for environmental releases of gene drive modified insects

Y. Devos, J. D. Mumford, M. B. Bonsall, D. C. M. Glandorf and H. D. Quemada,  Biotechnology Advances,  2021.
The ability to engineer gene drives (genetic elements that bias their own inheritance) has sparked enthusiasm and concerns. Engineered gene drives could potentially be used to address long-standing challenges in the control of insect disease vectors, agricultural pests and ...
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CRISPR-Cas and Its Wide-Ranging Applications: From Human Genome Editing to Environmental Implications, Technical Limitations, Hazards and Bioethical Issues

R. Piergentili, A. Del Rio, F. Signore, F. U. Ronchi, E. Marinelli and S. Zaami,  Cells,  10:24. 2021.
The CRISPR-Cas system is a powerful tool for in vivo editing the genome of most organisms, including man. During the years this technique has been applied in several fields, such as agriculture for crop upgrade and breeding including the creation of allergy-free foods, for ...
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Conservation pest control with new technologies: public perceptions

E. A. MacDonald, M. B. Neff, E. Edwards, F. Medvecky and J. Balanovic,  Journal of the Royal Society of New Zealand,  2021.
We conducted eleven focus groups in New Zealand to explore three questions about novel technologies (gene drive and two others for comparison of pest control tools): (1) what are the risks/benefits? (2) how do they compare to current methods? and (3) who should be represented on ...
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Evaluating the Probability of CRISPR-based Gene Drive Contaminating Another Species

V. Courtier-Orgogozo, A. Danchin, P.-H. Gouyon and C. Boëte,  Evolutionary Applications,  Early Online. 2020.
he probability D that a given CRISPR-based gene drive element contaminates another, non-target species can be estimated by the following Drive Risk Assessment Quantitative Estimate (DRAQUE) Equation: D = (hyb + transf).express.cut.flank.immune.nonextinct with ...
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RSPM No. 27 Guidelines for Importation and Confined Field Release of Transgenic Arthropods in NAPPO Member Countries

NAPPPO,  NAPPO Regional Standards for Phytosanitary Measures,  2007.
This Standard is designed to provide guidance to NAPPO member countries on the importation and confined field release of transgenic arthropods that are known plant pests or have the potential to affect plant health. This includes transgenic arthropods used for biological control ...
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Guidelines for the export, shipment, import and release of biological control agents and other beneficial organisms

International Plant Protection Convention,  Food and Agriculture Organization,  2005.
This standard provides guidelines for risk management related to the export, shipment, import and release of biological control agents and other beneficial organisms. It lists the related responsibilities of contracting parties to the IPPC, national plant protection organizations ...
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