Keywords: risk assessement

CRISPR-based gene drives for combatting malaria: Need for an early stage technology assessment.

Liebert, W.,  AREA-WIDE INTEGRATED PEST MANAGEMENT: Development and Field Application,  2021.
The potential power of CRISPR-based gene drives makes it necessary to engage in science and technology assessment already in early stages of research and development. In order to argue for efforts to address this urgent need, gene drives to combat malaria-transmitting mosquitoes ...
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Can a population targeted by a CRISPR-based homing gene drive be rescued?

N. O. Rode, V. Courtier-Orgogozo and F. Débarre,  G3-Genes Genomes Genetics,  2020.
N. O. Rode, V. Courtier-Orgogozo and F. Débarre (2020). G3 doi: 10.1534/g3.120.401484 Developing countermeasures is important to control the spread of gene drives, should they result in unanticipated damages. One proposed countermeasure is the introduction of individuals ...
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The EU not ready for the release of Gene drive organisms into the environment.

Pensoft Publishers,  ScienceDaily,  2020.
In their study, published in the open-access journal BioRisk, an international group of scientists led by Marion Dolezel from the Environment Agency Austria, discuss the potential risks and impacts on the environment.
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EFSA discusses risk assessment of gene drives

C. Then,  Testbiotech,  2020.
The European Food Safety Authority (EFSA) carried out a public consultation on guidance for the risk assessment of so-called gene drives at the request of the EU Commission. At the same time, a new Testbiotech scientific paper was accepted after peer review. The paper shows that ...
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Alternative Techniques and Options for Risk Reduction of Gene Drives

Bernd Giese, Arnim von Gleich and Johannes L. Frieß,  Gene Drives at Tipping Points,  2020.
In this chapter, we analyse and compare different types of gene drives as well as promising alternative approaches that may provide a reduced risk.
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Steps Towards a Precautionary Risk Governance of SPAGE Technologies Including Gene-Drives

Arnim von Gleich,  Gene Drives at Tipping Points,  2020.
In view of the rapid dynamics of genetic engineering development (in particular regarding the ‘new gene-technologies’ gene editing, self-propagating artificial genetic elements (SPAGESelf-Propagating Artificial Genetic Elements (SPAGE)) and synthetic biology), the question is ...
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Can a population targeted by a CRISPR-based homing gene drive be rescued?

N. O. Rode, V. Courtier-Orgogozo and F. Débarre,  bioRxiv,  2020.03.17.995829. 2020.
CRISPR-based homing gene drive is a genetic control technique aiming to modify or eradicate natural populations through the release of individuals carrying an engineered piece of DNA that can be inherited by all their progeny. Developing countermeasures is important to control ...
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