Keywords: Schistosomiasis

Public health concerns over gene-drive mosquitoes: will future use of gene-drive snails for schistosomiasis control gain increased level of community acceptance?

D. O. Famakinde,  Pathogens and Global Health,  2020.
With the advent of CRISPR (clustered regularly interspaced short palindromic repeat)-based gene drive, present genetic research in schistosomiasis vector control envisages the breeding and release of transgenic schistosome-resistant (TSR) snail vectors to curb the spread of the ...
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Gene drives for schistosomiasis transmission control

T. Maier, N. J. Wheeler, E. K. O. Namigai, J. Tycko, R. E. Grewelle, Y. Woldeamanuel, K. Klohe, J. Perez-Saez, S. H. Sokolow, G. A. De Leo, T. P. Yoshino, M. Zamanian and J. Reinhard-Rupp,  PLoS Neglected Tropical Diseases,  13:e0007833. 2019.
Schistosomiasis is one of the most important and widespread neglected tropical diseases (NTD), with over 200 million people infected in more than 70 countries; the disease has nearly 800 million people at risk in endemic areas. Although mass drug administration is a ...
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Evolutionary simulations of Z-linked suppression gene drives

L. Holman,  Proceedings of the Royal Society B-Biological Sciences,  286:1-9. 2019.
Synthetic gene drives may soon be used to suppress or eliminate populations of disease vectors, pathogens, invasive species, and agricultural pests. Recent proposals have focused on using Z-linked gene drives to control species with ZW sex determination, which include ...
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