
Keywords: simulans
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The fate of a suppressed X-linked meiotic driver: experimental evolution in Drosophila simulansH. Bastide, D. Ogereau, C. Montchamp-Moreau and P. R. Gérard, Chromosome Research, 2022.![]() Sex-ratio (SR) meiotic drivers are X-linked selfish genetic elements that promote their own transmission by preventing the production of Y-bearing sperm, which usually lowers male fertility. The spread of SR drivers in populations is expected to trigger the evolution of unlinked ... Keywords: drosophila, gene drive evolution, gene drive natural, meiotic drive, selective sweep, sex chromosomes, simulans, Y chromosome variation |
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Rapid evolutionary dynamics of an expanding family of meiotic drive factors and their hpRNA suppressorsJ. Vedanayagam, C. J. Lin and E. C. Lai, Nature Ecology and Evolution, 2021.![]() Meiotic drivers are a class of selfish genetic elements whose existence is frequently hidden due to concomitant suppressor systems. Accordingly, we know little of their evolutionary breadth and molecular mechanisms. Here, we trace the evolution of the Dox meiotic drive system in ... Keywords: drosophila, gene drive evolution, gene drive natural, meiotic drive, selective sweep, sex chromosomes, simulans, Y chromosome variation |
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Satellite DNA-mediated diversification of a sex-ratio meiotic drive gene family in DrosophilaC. A. Muirhead and D. C. Presgraves, Nature Ecology & Evolution, 2021.![]() Sex chromosomes are susceptible to the evolution of selfish meiotic drive elements that bias transmission and distort progeny sex ratios. Conflict between such sex-ratio drivers and the rest of the genome can trigger evolutionary arms races resulting in genetically suppressed ... Keywords: drosophila, gene drive evolution, gene drive natural, meiotic drive, selective sweep, sex chromosomes, simulans, Y chromosome variation |
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Red queen’s race: rapid evolutionary dynamics of an expanding family of meiotic drive factors and their hpRNA suppressorsJ. Vedanayagam, C.-J. Lin and E. C. Lai, bioRxiv, 2021.08.05.454923. 2021.![]() Meiotic drivers are a class of selfish genetic elements that are widespread across eukaryotes. Their activities are often detrimental to organismal fitness and thus trigger drive suppression to ensure fair segregation during meiosis. Accordingly, their existence is frequently ... Keywords: drosophila, gene drive evolution, gene drive natural, meiotic drive, selective sweep, sex chromosomes, simulans, Y chromosome variation |
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Sex-ratio meiotic drive shapes the evolution of the Y chromosome in Drosophila simulansQ. Helleu, C. Courret, D. Ogereau, K. L. Burnham, N. Chaminade, M. Chakir, S. Aulard and C. Montchamp-Moreau, Molecular Biology and Evolution, 36:2668-2681. 2019.![]() The recent emergence and spread of X-linked segregation distorters-called "Paris" system-in the worldwide species Drosophila simulans has elicited the selection of drive-resistant Y chromosomes. Here, we investigate the evolutionary history of 386 Y chromosomes originating from ... Keywords: drosophila, gene drive evolution, gene drive natural, meiotic drive, selective sweep, sex chromosomes, simulans, Y chromosome variation |

Contact
David O’Brochta
Foundation for the
National Institutes of Health
geneconvenevi@fnih.org
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