Keywords: spread

Pulled, pushed or failed: the demographic impact of a gene drive can change the nature of its spatial spread

L. Kläy, L. Girardin, V. Calvez and F. Débarre,  arXiv,  2022.
Understanding the temporal spread of gene drive alleles -- alleles that bias their own transmission -- through modeling is essential before any field experiments. In this paper, we present a deterministic reaction-diffusion model describing the interplay between demographic and ...
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Predicting the spread and persistence of genetically modified dominant sterile male mosquitoes

A. Ickowicz, S. D. Foster, G. R. Hosack and K. R. Hayes,  Parasites and Vectors,  14:480. 2021.
Reproductive containment provides an opportunity to implement a staged-release strategy for genetic control of malaria vectors, in particular allowing predictions about the spread and persistence of (self-limiting) sterile and male-biased strains to be compared to outcomes before ...
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Researchers’ Plan To Release Genetically Engineered American Chestnut Trees in Forests Will Set Dangerous Precedents If Approved

Global Justice Ecology Project,  Common Dreams,  2020.
Researchers are working with the United States Department of Agriculture (USDA) to finalize a petition requesting the unprecedented approval of a genetically engineered (GE or genetically modified) tree designed to be planted in our forests and spread freely in the wild. Once the ...
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Gene Drive Basics – Characteristics and Properties

GeneConvene Global Collaborative,  GeneConvene Global Collaborative,  2020.
This short video covers the concept of 'drive strength', 'drive thresholds', 'spreading', 'resistance' and describes two strategies by which transmission advantages can be achieved.  The video is intended to provide additional insights into the technology to enable and encourage ...
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Optimal control and analysis of a modified trojan Y-Chromosome strategy

M. A. Beauregard, R. D. Parshad, S. Boon, H. Conaway, T. Griffin and J. J. Lyu,  Ecological Modelling,  416. 2020.
The Trojan Y Chromosome (TYC) strategy is a promising eradication method that attempts to manipulate the female to male ratio to promote the reduction of the population of an invasive species. The manipulation stems from an introduction of sex-reversed males, called supermales, ...
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The optimal implementation of the Trojan Y chromosome eradication strategy of invasive species

M. R. Kelly and X. Y. Wang,  Journal of Biological Systems,  25:399-418. 2017.
Invasive aquatic species continue to be a persistent problem around the world. The Trojan Y Chromosome (TYC) eradication strategy has recently been developed to help fight the problem in aquatic systems by targeting only the invasive species, sparing native marine stock. It ...
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