Keywords: Sry
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Generation of Gene Drive Mice for Invasive Pest Population SuppressionM. D. Bunting, C. Pfitzner, L. Gierus, M. White, S. Piltz and P. Q. Thomas, Applications of Genome Modulation and Editing, 2022.
Gene drives are genetic elements that are transmitted to greater than 50% of offspring and have potential for population modification or suppression. While gene drives are known to occur naturally, the recent emergence of CRISPR-Cas9 genome-editing technology has enabled ... |
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Meet Cosmo, the gene-edited Crispr calfS. D. McClain, Capital Press, 2020.
Cosmo was the grand finale of a series of experiments to create a line of genome-edited cattle tailored for the beef industry. He was designed to produce 75% male offspring. |
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A Crispr calf is born. It’s definitely a boyM. Molteni, WIRED, 2020.
M. Molteni (2020). Wired. UC Davis scientists spent years editing a sex-determining gene into bovine embryos. In April, Cosmo arrived—and his DNA reveals how far the field has to go. This type of sex ratio distortion results in gene drive and is also being considered to help ... |
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Meet the first genetically modified bull. Why did scientists change itJ. Kessler, Free News, 2020.
J. Kessler (2020). Free News. UC Davis scientists have successfully introduced a bovine embryo, or the bovine SRY gene, which is responsible for the development of the male. This is the first demonstration of targeted gene insertion for large DNA sequences through embryo-mediated ... |
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Scientists use CRISPR technology to insert sex-determining geneA. Quinton, Phys Org, 2020.
A. Quinton (2020). Phys Org. Scientists at the University of California, Davis, have successfully produced a bull calf, named Cosmo, who was genome-edited as an embryo so that he'll produce more male offspring. The research was presented in a poster on July 23 at the American ... |
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Exploring Stakeholder Perspectives on the Development of a Gene Drive Mouse for Biodiversity Protection on Islands: Workshop ReportM. Farooque, S. K. Barnhill-Dilling, J. Shapiro and J. Delborne, North Carolina State University, 2019.
The “Exploring Stakeholder Perspectives on the Development of a Gene Drive Mouse for Biodiversity Protection” workshop was held on the North Carolina State University campus in Raleigh, NC on March 7-8, 2019, aiming to convene a diverse group of stakeholders, scientists, ... |
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Genetic pest management technologies to control invasive rodentsD. Kanavy and D. Threadgill, Island invasives: scaling up to meet the challenge, 2019.
Many strategies exist to manage invasive pests on islands, ranging from poison to trapping, with varying degrees of success. Genetic technologies are increasingly being applied to insect pests, but so far, not to vertebrates. We are implementing a genetic strategy to eradicate ... |
