Keywords: synthetic species
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Scientists design new gene drive to stop the transmission of devastating diseasesE. Henderson, AZO Life Sciences, 2021.
CRISPR-based technologies offer enormous potential to benefit human health and safety, from disease eradication to fortified food supplies. As one example, CRISPR-based gene drives, which are engineered to spread specific traits through targeted populations, are being developed ... |
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Synthetic SPECIES developed for use as a confinable gene driveUniversity of California - San Diego, ScienceDaily, 2021.
CRISPR-based technologies offer enormous potential to benefit human health and safety, from disease eradication to fortified food supplies. As one example, CRISPR-based gene drives, which are engineered to spread specific traits through targeted populations, are being developed ... |
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Engineered reproductively isolated species drive reversible population replacementA. Buchman, I. Shriner, T. Yang, J. Liu, I. Antoshechkin, J. M. Marshall, M. W. Perry and O. S. Akbari, Nature Communications, 12:3281. 2021.
Engineered reproductive species barriers are useful for impeding gene flow and driving desirable genes into wild populations in a reversible threshold-dependent manner. However, methods to generate synthetic barriers are lacking in advanced eukaryotes. Here, to overcome this ... |
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‘Clever Approach’: Scientists Create GM-Free Organisms Using Genetic EngineeringA. Paleja, The WIRE, 2021.
Farther to the north, researchers at the University of Minnesota have developed a novel way to resolve this problem. They used genetic engineering to create organisms for release that are not genetically modified. Maciej Maselko was a postdoctoral associate at the university ... |
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Fruit fly breakthrough puts killer mozzies on noticeV. Tressider, The Lighthouse, 2020.
A new designer fruit fly paves the way for scientists to replace disease-carrying mosquitoes with harmless, genetically modified versions, says Macquarie University researcher Dr Maciej Maselko. |
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Engineered Gene Drives: State of Research Webinar Series by The GeneConvene Global Collaborative September-October 2020David O'Brochta and Hector Quemada, GeneConvene Global Collaborative, 2020.
A series of technical webinars on engineered gene drive technology research and development given by leading researchers in the field. |
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Mutant mosquitoes: GM insects ‘engineered’ in ‘new approach to pest control’T. Fish, EXPRESS, 2020.
This cutting-edge research provides the foundations for plans to prevent genetically modified organisms from reproducing with wild organisms. |
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Engineering multiple species-like genetic incompatibilities in insectsM. Maselko, N. Feltman, A. Upadhyay, A. Hayward, S. Das, N. Myslicki, A. J. Peterson, M. B. O’Connor and M. J. Smanski, Nature Communications, 11:4468. 2020.
Here, we demonstrate a general approach to create engineered genetic incompatibilities (EGIs) in the model insect Drosophila melanogaster. |
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Engineering speciation events in insects may be used to control harmful pestsUniversity of Minnesota, Phys Org, 2020.
A team of scientists led by Mike Smanski, Ph.D., in the College of Biological Sciences (CBS) has generated speciation events in fruit flies so that engineered strains can reproduce normally with each other, but mating with unmodified flies results in non-viable offspring. |
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GeneConvene Global Collaborative Webinar SeriesDavid O'Brochta and Hector Quemada, GeneConvene Global Collaborative, 2020.
This is a series of public scientific and technical seminars by researchers actively involved in the research and development of engineered gene drive and related systems. Presentations will be aimed at other researchers and scientists, highlighting the latest investigations in ... |
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Engineered Reproductively Isolated Species Drive Reversible Population ReplacementA. Buchman, I. Shriner, T. Yang, J. Liu, I. Antoshechkin, J. M. Marshall, M. W. Perry and O. S. Akbari, bioRxiv, 2020.08.09.242982. 2020.
Engineered reproductive species barriers are useful for impeding gene flow and driving desirable genes into wild populations in a reversible threshold-dependent manner. We engineer multiple reproductively isolated SPECIES and demonstrate their threshold-dependent gene drive ... |
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Genetic control of Invasive carpMAISRC, Minnesota Aquatic Invasive Species Research Center, 2019.
This project focuses on a novel method of biocontrol for common carp which will complement existing technologies by introducing a synthetic species-like barrier to reproduction. Researchers will use programmable transcription activators to drive lethal embryonic overexpression of ... |
