A synthetic maternal-effect selfish genetic element drives population replacement in DrosophilaChen, CHH, H. X.; Ward, C. M.; Su, J. T.; Schaeffer, L. V.; Guo, M.; Hay, B. A., Science, 316:597-600. 2007.
One proposed strategy for controlling the transmission of insect-borne pathogens uses a drive mechanism to ensure the rapid spread of transgenes conferring disease refractoriness throughout wild populations. Here, we report the creation of maternal-effect selfish genetic elements ...
Keywords: aides-aegypti, Anopheles gambiae, behavior, complex, dynamics, history 2000-present, malaria parasite, mosquitos, resistance, Science & Technology - Other Topics, systems, vectors
Foundation for the
National Institutes of Health