target site recognition Archives • GeneConvene Virtual Institute

Keywords: target site recognition

Evolution of divergent DNA recognition specificities in VDE homing endonucleases from two yeast species

Posey, KLK, V.; Burt, A.; Gimble, F. S., Nucleic Acids Research, 32:3947-3956. 2004.

Homing endonuclease genes (HEGs) are mobile DNA elements that are thought to confer no benefit to their host. They encode site-specific DNA endonucleases that perpetuate the element within a species population by homing and disseminate it between species by horizontal transfer. ...
Keywords: crystal-structure, DNA, gene drive ecology, gene drive evolution, gene drive natural, group-i introns, ho endonuclease, homing endonuceases, horizontal transfer, intercellular mobility, nuclear rdna, plants, ribosomal-rna genes, saccharomyces-cerevisiae, target site recognition

Homing endonuclease genes: the rise and fall and rise again of a selfish element

Burt, AK, V., Current Opinion in Genetics & Development, 14:609-615. 2004.

Homing endonuclease genes (HEGs) are selfish genetic elements that spread by first cleaving chromosomes that do not contain them and then getting copied across to the broken chromosome as a byproduct of the repair process. The success of this strategy will depend on the ...
Keywords: crystal-structure, DNA, gene drive ecology, gene drive evolution, gene drive natural, group-i introns, ho endonuclease, homing endonuceases, horizontal transfer, intercellular mobility, nuclear rdna, plants, ribosomal-rna genes, saccharomyces-cerevisiae, target site recognition