Keywords: technologies

A Y-chromosome shredding gene drive for controlling pest vertebrate populations

Prowse, TAAA, F.; Cassey, P.; Thomas, P.; Ross, J. V.,  eLife,  8:19. 2019.
Self-replicating gene drives that modify sex ratios or infer a fitness cost could be used to control populations of invasive alien species. The targeted deletion of Y sex chromosomes using CRISPR technology offers a new approach for sex bias that could be incorporated within ...
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Controlling invasive rodents via synthetic gene drive and the role of polyandry

Manser, AC, S. J.; Sutter, A.; Blondel, D. V.; Serr, M.; Godwin, J.; Price, T. A. R.,  Proceedings of the Royal Society B-Biological Sciences,  286:9. 2019.
House mice are a major ecosystem pest, particularly threatening island ecosystems as a non-native invasive species. Rapid advances in synthetic biology offer new avenues to control pest species for biodiversity conservation. Recently, a synthetic sperm-killing gene drive ...
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Sustainability as a framework for considering gene drive mice for invasive rodent eradication

Barnhill-Dilling, SKS, M.; Blondel, D. V.; Godwin, J.,  Sustainability,  11:1334. 2019.
Gene drives represent a dynamic and controversial set of technologies with applications that range from mosquito control to the conservation of biological diversity on islands. Currently, gene drives are being developed in mice that may one day serve as an important tool for ...
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