Widespread haploid-biased gene expression enables sperm-level natural selectionK. Bhutani, K. Stansifer, S. Ticau, L. Bojic, A.-C. Villani, J. Slisz, C. M. Cremers, C. Roy, J. Donovan, B. Fiske and R. C. Friedman, Science, eabb1723. 2021.
Here, we show that a large class of mammalian genes are not completely shared across these bridges. We term these genes “genoinformative markers” (GIMs) and show that a subset can act as selfish genetic elements that spread alleles unevenly through murine, bovine, and human ...
Keywords: gene drive natural, genoinformative markers, mammals, meiotic drive, selfish genetic element, sperm, t haplotype, testis, transmission ratio distortion
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