Keywords: toxin-antidote drive
Evading resistance to gene drivesR. Gomulkiewicz, M. L. Thies and J. J. Bull, Genetics, 217. 2021.
Here, we develop mathematical and computational models to identify conditions under which suppression drives will evade resistance, even if resistance is present initially. Previous models assumed resistance is allelic to the drive. We relax this assumption and show that linkage ...
Keywords: CRISPR, gene drive synthetic, homing drive, nonallelic resistance, population suppression, toxin-antidote drive
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