Keywords: translocation
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Modeling confinement and reversibility of threshold-dependent gene drive systems in spatially-explicit Aedes aegypti populationsH. M. Sánchez C, J. B. Bennett, S. L. Wu, G. Rašić, O. S. Akbari and J. M. Marshall, BMC Biology, 18:50. 2020.
Here, we model hypothetical releases of two recently engineered threshold-dependent gene drive systems—reciprocal chromosomal translocations and a form of toxin-antidote-based underdominance known as UDMEL—to explore their ability to be confined and remediated. |
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Sterility introduced by release of genetically altered males to a domestic population of Aedes aegypti at the Kenya coastP. T. McDonald, W. Hausermann and N. Lorimer, Am J Trop Med Hyg, 26:553-61. 1977.
A decade ago the concept of the sterile insect release method (SIRM) of control was generally limited to the induction of sterility through either radiation or chemical treatment. Since then the concept of genetic control has broadened to in dude the SIRM of natural sterility as ... |
