
Keywords: Two-locus underdominance
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Modeling the mutation and reversal of engineered underdominance gene drivesEdgington, MPA, Luke S., Journal of Theoretical Biology, 479:14-21. 2019.![]() A range of gene drive systems have been proposed that are predicted to increase their frequency and that of associated desirable genetic material even if they confer a fitness cost on individuals carrying them. Engineered underdominance (UD) is such a system and, in one version, ... Keywords: gene drive genetics, gene drive models, gene drive synthetic, Loss of function, Mosquito control, Population genetics, Two-locus underdominance, underdominance |

Contact
David O’Brochta
Foundation for the
National Institutes of Health
geneconvenevi@fnih.org
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