Keywords: vector-borne diseases
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Ethics and vector-borne diseasesWHO, WHO Guidance, 2020.
The guidance was developed by an international group of experts in vector control, infectious disease ethics, maternal and child health, ecology and climate change, research and vaccine development, and public health communication. It examines a broad range of ethical ... |
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CRISPR/Cas9 gene drive technology to control transmission of vector-borne parasitic infectionsM. Nateghi Rostami, Parasite Immunology, preprint:e12762. 2020.
Gene drive is the process of copying of an endonuclease-containing cassette that leads to increased frequency of inheritance of the desired traits in a targeted population. CRISPR/Cas9 technology is advancing genetic manipulation of insects in the field of gene drive ... |
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Transgenic Mosquitoes – Fact or Fiction?Wilke, A. B. B., J. C. Beier and G. Benelli, Trends in Parasitology, 34:456-465. 2018.
echnologies for controlling mosquito vectors based on genetic manipulation and the release of genetically modified mosquitoes (GMMs) are gaining ground. However, concrete epidemiological evidence of their effectiveness, sustainability, and impact on the environment and nontarget ... |
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Site-specific selfish genes as tools for the control and genetic engineering of natural populationsBurt, A, Proceedings of the Royal Society B-Biological Sciences, 270:921-928. 2003.
Site-specific selfish genes exploit host functions to copy themselves into a defined target DNA sequence, and include homing endonuclease genes, group II introns and some LINE-like transposable elements. If such genes can be engineered to target new host sequences, then they can ... |
