
Keywords: wAlbB
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Analysing inhibition of dengue virus in Wolbachia-infected mosquito cells following the removal of WolbachiaM. Hussain, K. Etebari and S. Asgari, Virology, 581:48-55. 2023.![]() Wolbachia pipientis is known to block replication of positive sense RNA viruses. Previously, we created an Aedes aegypti Aag2 cell line (Aag2.wAlbB) transinfected with the wAlbB strain of Wolbachia and a matching tetracycline-cured Aag2.tet cell line. While dengue virus (DENV) ... Keywords: Aedes, aegypti, dengue, genetic biocontrol, wAlbB, wolbachia |
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Wolbachia inhibits ovarian formation and increases blood feeding rate in female Aedes aegyptiM.-J. Lau, P. A. Ross, N. M. Endersby-Harshman, Q. Yang and A. A. Hoffmann, PLOS Neglected Tropical Diseases, 16:e0010913. 2022.![]() Author summary Wolbachia bacteria reduce the transmission of dengue and other arboviruses transmitted by their mosquito hosts once they have invaded host populations. This invasion process is being undertaken in Aedes aegypti mosquito populations throughout the world but can be ... Keywords: Aedes, aegypti, dengue, genetic biocontrol, wAlbB, wolbachia |
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Studies on the fitness characteristics of wMel- and wAlbB-introgressed Aedes aegypti (Pud) lines in comparison with wMel- and wAlbB-transinfected Aedes aegypti (Aus) and wild-type Aedes aegypti (Pud) linesC. Sadanandane, K. Gunasekaran, D. Panneer, S. K. Subbarao, M. Rahi, B. Vijayakumar, V. Athithan, A. Sakthivel, S. Dinesh and P. Jambulingam, Frontiers in Microbiology, 13:947857. 2022.![]() Wolbachia, an intracellular maternally transmitted endosymbiont, has been shown to interfere with the replication of dengue virus in Aedes aegypti mosquitoes. The Wolbachia-transinfected Ae. aegypti has been currently released in many countries to test its effectiveness in ... Keywords: Aedes, aegypti, dengue, genetic biocontrol, wAlbB, wolbachia |
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Wolbachia wAlbB inhibits bluetongue and epizootic hemorrhagic fever viruses in Culicoides midge cellsM. L. Matthews, H. O. Covey, B. S. Drolet and C. L. Brelsfoard, Medical and Veterinary Entomology, 2022.![]() Abstract Culicoides midges are hematophagous insects that transmit arboviruses of veterinary importance. These viruses include bluetongue virus (BTV) and epizootic hemorrhagic fever virus (EHDV). The endosymbiont Wolbachia pipientis Hertig spreads rapidly through insect host ... Keywords: Aedes, aegypti, dengue, genetic biocontrol, wAlbB, wolbachia |
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Persistent Spodoptera frugiperda rhabdovirus infection in Sf9 cells is not restricted by Wolbachia wMelPop-CLA and wAlbB strains and is targeted by the RNAi machineryR. Parry, H. de Malmanche and S. Asgari, Virology, 563:82-87. 2021.![]() The endosymbiotic bacterium Wolbachia pipientis confers RNA virus refractoriness in Drosophila and Aedes mosquitoes. Questions remain about the Wolbachia-virus restriction phenotype and how extensive this phenomenon may be within other arthropods. Here, we generated two ... Keywords: Aedes, aegypti, dengue, genetic biocontrol, wAlbB, wolbachia |
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Establishment of Wolbachia Strain wAlbB in Malaysian Populations of Aedes aegypti for Dengue ControlW. A. Nazni, A. A. Hoffmann, A. NoorAfizah, Y. L. Cheong, M. V. Mancini, N. Golding, G. M. R. Kamarul, M. A. K. Arif, H. Thohir, H. NurSyamimi, M. Z. ZatilAqmar, M. NurRuqqayah, A. NorSyazwani, A. Faiz, F.-R. M. N. Irfan, S. Rubaaini, N. Nuradila, N. M. N, Current Biology, 29:4241-4248.e5. 2019.![]() Dengue has enormous health impacts globally. A novel approach to decrease dengue incidence involves the introduction of Wolbachia endosymbionts that block dengue virus transmission into populations of the primary vector mosquito, Aedes aegypti. The wMel Wolbachia strain has ... Keywords: Aedes, aegypti, dengue, genetic biocontrol, wAlbB, wolbachia |

Contact
David O’Brochta
Foundation for the
National Institutes of Health
geneconvenevi@fnih.org
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