Pest Species
Anopheles gambiae
Human malaria mosquito
Tanzania
Dar es Salaam
Control Measure
Synopsis
- Transmission Zero is a gene drive research and development program involving Imperial College London in the United Kingdom, the Ifakara Health Institute and the National Institute of Medical Research in Tanzania
- They are developing gene drive technology that will prevent Anopheles gambiae from transmitting the malaria parasite.
- The first genetically modified mosquitoes produced in Africa were produced by the Transmission Zero team at IHI in Tanzania. These did not contain a gene drive system.
- There have been no releases of gene drive-containing mosquitoes
Learn More
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Scientists engineer mosquitoes that can’t spread malariaImperial College London, Phys Org, 2022.
Scientists have engineered mosquitoes that slow the growth of malaria-causing parasites in their gut, preventing transmission of the disease to humans. The genetic modification causes mosquitoes to produce compounds in their guts that stunt the growth of parasites, meaning they ... |
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Gene drive mosquitoes can aid malaria elimination by retarding Plasmodium sporogonic developmentHoermann, Astrid, Habtewold, Tibebu, Selvaraj, Prashanth, Del Corsano, Giuseppe, Capriotti, Paolo, Inghilterra, Maria Grazia, Kebede, Temesgen M., Christophides, George K. and Windbichler, Nikolai, Science Advances, 2022.
Gene drives hold promise for the genetic control of malaria vectors. The development of vector population modification strategies hinges on the availability of effector mechanisms impeding parasite development in transgenic mosquitoes. We augmented a midgut gene of the malaria ... |
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First transgenic mosquito made in Africa by Transmission ZeroH. Dunning, Imperial College London, 2023.
Transmission Zero, a global scientific programme led by scientists at Imperial College London and the Ifakara Health Institute (IHI) of Tanzania, in partnership with the Tanzanian National Institute of Medical Research (NIMR), announces the generation of the first transgenic ... |
