Can gene drive-modified mosquitoes be controlled by current vector control tools?

Categories: Gene Drive Mosquitoes, Gene Drive Safety

Yes, depending upon the type of gene drive and extent of release. Insecticide resistance is not required for gene drive-modified mosquitoes to function successfully. Care is being taken not to introduce modifications that might increase insecticide resistance in the local mosquito population. For example, the gene drive construct can be introgressed into the genetic background of the local target species so that their other characteristics remain unchanged. Addittional methods for controlling gene drive-modified mosquitoes, including genetic mechanisms and small molecule approaches, also are being explored.

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