Most expressed concerns fall into a few major categories:
- Transboundary movement: Questions have been raised about the adequacy of current governance mechanisms to deal with the implications of movement of gene drive-modified organisms across national boundaries.
- Consent: For release of gene drive-modified organisms that will spread beyond the initial release site, there are questions about from whom prior consent should be obtained, as well as appropriate mechanisms for obtaining that consent.
- Environmental effects: Some stakeholders are concerned that the effects of gene drive-modified organisms will be unpredictable and that risk assessment methods will not be able to estimate the potential long-term effects to the environment.
- Extinctions: Some express concerns about the population suppression technologies might result in eradication of the target species.
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