Gene Drive in the News

A curated collection of articles from the popular press

Why are scientists creating genetically modified mosquitoes?

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The Week Staff,  The Week,  2020-07-27 11:35:19.
The Week Staff. The Week (2020). Scientists plan to release altered mosquitoes designed to sabotage the species' ability to reproduce. Is this safe? Here's everything you need to know:

The future of beef might be a sausage fest

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N. Johnson,  grist,  2020-07-24 21:00:33.
N. Johnson. (2020) grist. A media report on the creation of a cow with a sex ratio altering genetic change expected to lead to 3/4 of the cow's offspring being males. This type of sex ratio distortion results in gene drive and is also being considered to help control populations of invasive mammals.

Meet Cosmo the Frankenbull: Scientists genetically engineer a bull calf so that 75 per cent of its offspring will be male

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J. Pinkstone,  Daily Mail,  2020-07-24 20:58:14.
J. Pinkstone (2020). Daily Mail. A media report on the creation of a cow with a sex ratio altering genetic change expected to lead to 3/4 of the cow's offspring being males. This type of sex ratio distortion results in gene drive and is also being considered to help control populations of invasive mammals.

A Crispr calf is born. It’s definitely a boy

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M. Molteni,  WIRED,  2020-07-24 16:25:14.
M. Molteni (2020). Wired. UC Davis scientists spent years editing a sex-determining gene into bovine embryos. In April, Cosmo arrived—and his DNA reveals how far the field has to go. This type of sex ratio distortion results in gene drive and is also being considered to help control populations of invasive mammals.

Meet the first genetically modified bull. Why did scientists change it

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J. Kessler,  Free News,  2020-07-23 20:52:51.
J. Kessler (2020). Free News. UC Davis scientists have successfully introduced a bovine embryo, or the bovine SRY gene, which is responsible for the development of the male. This is the first demonstration of targeted gene insertion for large DNA sequences through embryo-mediated genome editing in cattle. This type of sex ratio distortion results in gene drive and is also being considered to help control populations of invasive mammals.

Scientists use CRISPR technology to insert sex-determining gene

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A. Quinton,  Phys Org,  2020-07-23 16:21:10.
A. Quinton (2020). Phys Org. Scientists at the University of California, Davis, have successfully produced a bull calf, named Cosmo, who was genome-edited as an embryo so that he'll produce more male offspring. The research was presented in a poster on July 23 at the American Society of Animal Science meeting. This type of sex ratio distortion results in gene drive and is also being considered to help control populations of invasive mammals.

Tackling Dengue fever by turning female mosquitoes into males

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T. Sandle,  DIGTAL JOURNAL,  2020-07-22 21:00:41.
T. Sandle (2020). DIGTAL JOURNAL Genetic engineering appears to be the key for delivering mosquito control, according to new research. Scientists have successfully converted female mosquitoes into non-biting males.

Florida Keys delays vote on release of 750 million genetically engineered mosquitoes after public outcry

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D. Dukule,  Friends of the Earth,  2020-07-22 12:41:45.
The Florida Keys Mosquito Control District (FKMCD) today delayed its vote on the proposed release of genetically engineered (GE) mosquitoes due to concerns over COVID-19. The decision to delay the vote follows public outcry and scientific dispute over the risks posed to public health and the environment by this experimental release. The approval would have permitted the British company Oxitec to release 750 million GE mosquitoes over a two-year period in Monroe County, Florida, starting as soon as this summer.

Release of genetically modified mosquitoes in the Florida Keys put on hold

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D. Goodhue,  Miami Herald,  2020-07-21 19:27:08.
Opponents of a plan to release millions of genetically modified mosquitoes in the Florida Keys landed a temporary win on Tuesday.

EPA approves field trials of genetically modified mosquito

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A. Wernick,  WBFO npr,  2020-07-17 16:18:01.
The Environmental Protection Agency has given biotech company Oxitec the go-ahead to test the effectiveness of genetically modified mosquitoes in parts of Florida and Texas. Oxitec has been developing genetically modified mosquitoes in hopes of reducing local populations of mosquitoes that carry dengue fever, yellow fever and the Zika virus. About 750,000 people die each year from mosquito-borne illnesses, making the insect indirectly responsible for more human deaths than any other animal in the world.

An argument for gene drive technology to genetically control populations of insects like mosquitoes and locusts

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I. Ronai and B. Lovett,  The Conversation,  2020-07-14 18:15:19.
The fate of society rests in part on how humans navigate their complicated relationship with insects – trying to save “good” insects and control “bad” ones. Some insects, like mosquitoes, bite people and make them sick – remember Zika? Now the U.S. mosquito season is already in full swing, with over 10 cases of Dengue fever reported in the Florida Keys this year. Some insects, like bees, are pollinators that help produce our food. Others, like locusts, currently threaten crops in East Africa and Asia, preferring to eat our food instead. Insects have proven themselves extremely capable at evolving strategies to get around control methods, such as chemical insecticides and habitat modification, and current pest control technologies are simply not keeping up.

Researchers convert female mosquitoes to nonbiting males with implications for mosquito control

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Virginia Tech,  ScienceDaily,  2020-07-14 18:12:22.
Researchers convert female mosquitoes to nonbiting males with implications for mosquito control Virginia Tech researchers have proven that a single gene can convert female Aedes aegypti mosquitoes into fertile male mosquitoes and identified a gene needed for male mosquito flight

CSOs raise alarm over genetically-engineered mosquitoes in Nigeria

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A. Oboh,  Vanguard,  2020-07-11 17:41:57.
No fewer than 75 civil society organisations, CSOs, across the world have raised the alarm over moves to release genetically-modified mosquitoes in Nigeria, noting that the country was about to be used as a guinea pig for the project, which will endanger humans, biodiversity and to ecosystem balance. The CSOs noted that the shortcoming of transgenic mosquitoes was evident from the experiments done in Brazil and in Burkina Faso.

Three innovative technologies stopping malaria

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B. Muni,  The Borgen Project,  2020-07-09 14:47:45.
Malaria has plummeted by 40% fifteen years after 2000. A report that NCBI published attributed this to mosquito preventative measures like bed netting and insecticides. These interventions and practices, like wearing light color clothing, help at-risk populations fight malaria. However, mosquitos are learning to fight back. Resistance to insecticides is evolving in mosquitos and malaria continues to afflict millions. In 2018, there were still 228 million cases of malaria and 405,000 deaths. Over 90% of these cases and deaths occurred in Sub-Saharan Africa, but there are many interventions that have the potential to stop malaria. Here are three innovative technologies stopping malaria.

Groups warn against release of genetically-engineered mosquitoes in Nigeria

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C. Onyesi,  Daily Post,  2020-07-07 14:52:15.
C. Onyesi (2020). Daily Post. Over 75 Civil Society Organizations from Nigeria, Africa and the world have condemned moves to open the way for the release of genetically modified mosquitoes in Nigeria.

Beyone the buzz

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C. Watson,  The Journal Gazette,  2020-07-07 14:45:26.
Lately I have found I need to force myself to follow science stories about something besides the pandemic. A story I consider hopeful involves genetically modified mosquitoes; we are developing a new tool that can reduce disease and save lives. The goal is to dramatically reduce the mosquito population. Mosquitoes, by biting people and injecting some of their saliva, spread diseases such as yellow fever, dengue fever and malaria. Malaria kills about 600,000 people a year, mostly outside the U.S. The new tool being developed involves modifying the genes of male mosquitoes. The goal is to design a male mosquito that will behave typically, but whose female offspring die almost immediately.

Malaria: Over 75 CSOs raise alarm over plans to release nautically engineered mosquitoes

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News Agency of Nigeria,  WorldStage,  2020-07-06 14:56:01.
Mre than 75 Environmental Civil Society Organisations from Nigeria, Africa and other countries have condemned moves to open way for release of genetically modified mosquitoes to control malaria infection. The News Agency of Nigeria (NAN), reports that at a virtual meeting of the West African Integrated Vector Management Programme, on June 6, Mr Rufus Ebegba, Vice Chairman of the Programme said: “There is the need to accelerate the development of regulatory pathways for genetically based vector control methods such as transgenic mosquitoes.”

NGOs call for moratorium on controversial ‘gene drive organisms’

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N. Foote,  EURACTIV,  2020-07-03 14:50:12.
https://borgenproject.org/3-innovative-technologies-stopping-malaria/

GMO Mosquitoes to be launched in Florida

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Administration,  Editorials 360,  2020-07-01 14:38:18.
In June 2020, the Florida Division of Agriculture and Shopper Providers gave the go-ahead to a plan to launch thousands and thousands of genetically engineered mosquitoes within the Florida Keys this summer time to battle mosquito-borne diseases.1 The plan follows the EPA’s current granting of an experimental use allow (EUP) for the GMO (genetically modified organism) mosquitoes to allow them to be launched in Florida in 2020 and in Texas in 2021.2 The mosquitoes, engineered from the Aedes aegypti mosquito species,3 have been created by the U.S.-owned, Britain-based firm Oxitec, which originated as a spin-off firm from Oxford College and subsidiary of Intrexon.4 The corporate has additionally created genetically modified pink bollworm moths and GMO cabbage moths.

Nigerian government restates commitment to safety in applying modern biotechnology

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Agencies,  today ng,  2020-06-30 14:41:51.
The National Biosafety Management Agency (NBMA) has reiterated its commitment to ensure the safety of the public while applying modern biotechnology to boost food security and economic development of citizens. Dr Rufus Ebegba, Director-General, NBMA, gave the assurance at a meeting to review the National Guidelines of the Regulation of Gene Editing, on Tuesday in Abuja. Ebegba said the NBMA was amended in 2019, to include the application of gene drive, gene editing and synthetic biology and biosecurity which says: ”No person, institution or body shall carry out gene drive, gene editing and synthetic biology except with the approval of the agency,”.

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