This is an aggregation of scholarly literature from peer-reviewed journals, bioRxiv , medRxiv and arXiv preprint servers focused on natural and engineered selfish genetic elements and genetic biocontrol. New citations are added as they appear. This content is intended for anyone interested in the scholarly literature on gene drive and genetic biocontrol.
Tags:Anopheles, CRISPR, Malaria, Population suppression, Sex distorter
Larrosa-Godall, M., Ang, J.X.D., Leftwich, P.T. et al.,
Parasites & Vectors,
18.
2025.
Anopheles stephensi is a competent malaria vector mainly present in southern Asia and the Arabian Peninsula. Since 2012, it has invaded several countries of eastern Africa, creating an emerging risk of urban transmission. Urgent efforts are required to develop novel and more ...
Tags:Selfish genetic elements, Toxin-antidote
Nidamangala Srinivasa A., Campbell S., Venkatesan S., et al.,
PLOS Genetics,
21.
2025.
Diploid organisms, such as humans, have two copies of most genes. Only one copy, however, is transmitted through gametes (e.g., sperm and egg) to any given offspring. Alternate copies of the same gene are expected to be equally represented in the gametes, resulting in random ...
Tags:Aedes, Incompatible insect technique, Population suppression, Wolbachia
Ohm, J. R., Lynd, A., McGowan, A., et al.,
The American Journal of Tropical Medicine and Hygiene,
2025.
Male mosquitoes containing the endosymbiont Wolbachia (Wb+) can be used as a tool to suppress wild mosquito populations through a technique termed incompatible insect technique (IIT). IIT programs reduce wild mosquitoes via incompatible matings between released males and wild ...
Tags:Europe, Gene drive, Policy, Risk and safety
König, H., Kolleck, A., Sauter, A.,
TAB-Fokus,
48.
2025.
Gene drives have the potential to help solve major challenges, including the fight against invasive species or vector-borne diseases such as malaria. These hopes are offset by technical and scientific challenges as well as environmental risks. The policy brief TAB-Fokus no. 48 on ...
This is a curated collection of scholarly and non-scholarly materials that can be found in the Scholarly Literature and Media Coverage databases that are ‘opinion-heavy’. This collection is intended to capture the full range of thought and opinion about gene drive technologies.
Tags:Aedes, Genetically modified mosquitoes, Oceania, Oxitec, Risk and safety
Dr. Perran Stott-Ross,
University of Melbourne,
2025.
The British company Oxitec, in partnership with Australia's CSIRO, has announced plans to release genetically modified (GM) mosquitoes in Queensland. The initiative aims to reduce transmission of the dengue virus, as well as other pathogens spread by the Aedes aegypti mosquito by ...
Tags:Africa, Dengue, Vector control, Wolbachia
Samson Ogunlade, Adeshina Adekunle, Emma McBryde,
Frontiers,
12.
2025.
Dengue fever is a mosquito-borne viral disease that poses a significant public health concern globally. The disease is primarily transmitted by Aedes aegypti mosquitoes and the range of clinical manifestations vary from flu-like symptoms to more serious conditions such as dengue ...
Tags:Ethics, Gene drive, Malaria, Risk and safety
Laurie Zoloth,
The New York Times,
2024.
Bold ideas in science research used to thrill us; now they seem pretty threatening. When I have written about the ethics of genetically engineered mosquitoes to combat malaria, many of my friends have expressed alarm. “What if it goes badly wrong?” they ask. What if there are ...
Tags:Africa, Gene drive, Genetically modified organisms, Mosquitoes
Barbara Ntambirweki,
The Independent,
2024.
The Uganda Virus Research Institute is pressing forward with gene drive technology which provides a way to rapidly, permanently, and genetically modify wild animals or plants. Gene drive organisms, are a genetically modified organism (GMO) designed to spread a genetic ...
This is a database of print and digital media coverage of gene drive technologies and genetic biocontrol-related topics. This database is intended to serve experts and non-experts by capturing how gene drive/genetic biocontrol technologies and issues around the technologies are being represented, discussed, debated and evaluated by the public.
Tags:Gene drive, Malaria, Video
Reuters,
YouTube,
2025.
An international team of scientists are developing genetically modified mosquitoes that can slowly convert the entire wild population of mosquitoes resistant to transmitting malaria, the world’s most deadly disease.
Tags:Gene drive, Video
Biology for Everyone,
YouTube,
2025.
What Is Gene Drive? In this informative video, we will introduce you to the intriguing concept of gene drive, a revolutionary technology that enables the rapid transmission of specific traits within a species. We will break down the mechanics of how gene drive works, including ...
Tags:Africa, Gene drive, Malaria, Policy
African Union High-Level Panel on Emerging Technologies, APET Secretariat,
2025.
Malaria continues to impose a significant economic and public health burden on Africa. In 2021, the continent accounted for 95% of the global 247 million new malaria cases and 96% of the 619,000 malaria-related deaths. Notably, over three-quarters (77%) of these deaths occurred ...
Tags:Biodiversity/Conservation, Gene drive, Rodents, Video
Triangle Center for Evolutionary Medicine,
YouTube,
2025.
Biodiversity, human health, and food security can all be impacted by invasive rodents. These negative impacts are particularly seen on islands, where rodent eradications with traditional methods can sometimes fail due to evolutionary resistance. Gene drives may offer an approach ...
This is a collection of articles compiled from lay news sources, including newspapers, newscasts, blogs, and other non-academic communications. This content illustrates how genetic biocontrol and gene drive technologies are described in popular media.
Tags:Africa, Gene drive, Policy, Regulation, Target malaria
Charles Mugoya,
Target Malaria,
2025.
With support from the African Union Development Agency (AUDA-NEPAD), the African Union published its 1st APET report in 2018 which noted that that, while the existing mosquito control interventions have significantly reduced the burden of malaria across Africa, complementary new ...
Tags:Selfish genetic elements, Toxin-antidote
Stowers Institute for Medical Research,
PRNewswire,
2025.
Lurking within the genomes of nearly all species—including plants, fungi, and even humans—are genes that are passed from generation to generation with no clear benefit to the organism. Called "selfish" genes, they can sometimes be harmful or even lethal. A recent study from ...
Tags:Africa, Anopheles, Malaria, Modeling, Mosquitoes
Lisa Chamberland,
Outreach Network for Gene Drive Research,
2025.
As part of our work to develop new genetic approaches for malaria control, the University of California Malaria Initiative (UCMI) is studying mosquito movement and breeding patterns in São Tomé and Príncipe. In a study published last year, we investigated the dispersal ...
Tags:Africa, Gene drive, Malaria, Policy Ghana News Agency,
2025.
Ghana has expressed interest in exploring gene drive technology as a new approach to combatting malaria. The country is open to adopting technology that is cost-effective, efficient, harmless and has the potential to significantly reduce malaria transmission, especially in areas ...
