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About the GeneConvene Virtual Institute

The Virtual Institute is an initiative of the GeneConvene Global Collaborative, a program within the Foundation for the National Institutes of Health that advances best practices for genetic biocontrol technologies such as those using gene drive.

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All/Events/Gene Drive in the News
June 6, 2025

Unlocking Gene Drive in Agriculture

June 6, 2025

The Future of Gene Drive in Farming

June 3, 2025

We finally may be able to rid the world of mosquitoes. But should we?

April 21, 2025

Register: Environmental Monitoring Considerations For Gene Drive Modified Mosquitoes

December 5, 2023

Meeting Abstracts from the 5th B Chromosome Conference

December 13, 2019

24th Meeting of the Subsidiary Body on Scientific, Technical and Technological Advice of the CBD, May 18-23, 2020, Montreal, Canada

June 6, 2025

Unlocking Gene Drive in Agriculture

June 6, 2025

The Future of Gene Drive in Farming

June 3, 2025

We finally may be able to rid the world of mosquitoes. But should we?

Frequently Asked Questions

March 16, 2022/by Academic Web Pages

Gene Drive Basics

May 15, 2024/by Academic Web Pages

History of Gene Drive

May 15, 2024/by Academic Web Pages

Genetic Biocontrol Programs

July 24, 2024/by Academic Web Pages

Webinar Series

October 1, 2024/by Academic Web Pages

Academy

October 1, 2024/by Academic Web Pages

Regulation and Policy

October 1, 2024/by Academic Web Pages

Infographics

October 1, 2024/by Academic Web Pages

GeneConvene Global Collaborative on YouTube

December 10, 2024/by Academic Web Pages

Knowledgebase

Scholarly Literature

Scholarly Literature

This is an aggregation of scholarly literature from peer-reviewed journals,  bioRxiv , medRxiv and arXiv preprint servers focused on natural and engineered selfish genetic elements and genetic biocontrol. New citations are added as they appear. This content is intended for anyone interested in the scholarly literature on gene drive and genetic biocontrol.


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Influence of genetic factors of humans, mosquitoes and parasites, on the evolution of Plasmodium falciparum infections, malaria transmission and genetic control methods: a review of the literature

Tags: Genetics, Malaria, Resistance, Transmission distortion
Nikiema, S., Soulama, I., Ampofo, G.D. et al.,  BMC Medical Genomics,  18. 2025.
Despite significant progress, malaria remains a public health problem in many regions, particularly in sub-Saharan Africa. This situation is partly explained by the mosquito’s resistance to insecticides and the emergence of parasite resistance to antimalarial drugs. Indeed, in ...

Conflicting Kinesin-14s in a single chromosomal drive haplotype

Tags: Chromosomal drive, Selfish genetic elements
Meghan J Brady, Anjali Gupta, Jonathan I Gent, et al.,  Genetics,  2025.
In maize, there are 2 meiotic drive systems that target large heterochromatic knobs composed of tandem repeats known as knob180 and TR-1. The first meiotic drive haplotype, abnormal chromosome 10 (Ab10) confers strong meiotic drive (∼75% transmission as a heterozygote) and ...

Evaluating the performance of three packing methods for long-distance transport of sterile adult Aedes albopictus males

Tags: Aedes, Mosquitoes, Sterile insect technique (SIT)
Mamai, W., Puggioli, A., Wallner, T. et al.,  Scientific Reports,  15. 2025.
This study evaluated the performance of three packing methods for long distance transport of sterile adult Aedes albopictus males, considering the specific effects of pupal vs. adult irradiation and two compaction methods. The results indicated that while transportation ...

Intrinsically weak sex chromosome drive through sequential asymmetric meiosis

Tags: Chromosomal drive, Fruit fly, Selfish genetic elements
Xuefeng Meng, Yukiko M. Yamashita,  Science Advances,  11. 2025.
Meiotic drivers are selfish genetic elements that bias their own transmission, violating Mendel’s Law of Equal Segregation. It has long been recognized that sex chromosome–linked drivers present a paradox: Their success in transmission can severely distort populations’ sex ...

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Perspectives

Perspectives

This is a curated collection of scholarly and non-scholarly materials that can be found in the Scholarly Literature and Media Coverage databases that are ‘opinion-heavy’.  This collection is intended to capture the full range of thought and opinion about gene drive technologies.


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Gene editing, extinction and ethics: Why open conversation is key

Tags: Ethics, Gene editing
Gabriela Harrod,  ASU News,  2025.
In a new paper published in Science, researchers are challenging one of conservation’s deepest assumptions — that extinction is always a failure to be avoided. With new genome-editing tools making it technically possible to eliminate entire species, the question is no longer ...

Commentary on Gene drive: Communication, hype, and the publics

Tags: Gene drive, Stakeholder engagement
Third World Network,  GMWatch,  2025.
An article in the Journal of Medical Entomology critically reflects on the hype surrounding gene drive technologies, a novel self-spreading form of genetic modification that is designed to engineer entire populations of wild species. The author, a specialist in vector-borne ...

Hordes of genetically modified insects set to be released in Australia: ‘They can smell you’

Tags: Genetically modified mosquitoes, Oceania, Oxitec, Sex distorter
Michael Dahlstrom,  Yahoo News,  2025.
Dengue fever is at record levels around the globe, with this trend now beginning to be reflected in Australia as the mosquito species that carries the virus spreads. It means a simple bite could soon trigger symptoms worse than an annoying itch, with victims often experiencing ...

3 reasons why the release of GM mosquitoes in Queensland is risky

Tags: Aedes, Genetically modified mosquitoes, Oceania, Oxitec, Risk and safety
Dr. Perran Stott-Ross,  University of Melbourne,  2025.
The British company Oxitec, in partnership with Australia's CSIRO, has announced plans to release genetically modified (GM) mosquitoes in Queensland. The initiative aims to reduce transmission of the dengue virus, as well as other pathogens spread by the Aedes aegypti mosquito by ...

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Multimedia

Multimedia

This is a database of print and digital media coverage of gene drive technologies and genetic biocontrol-related topics. This database is intended to serve experts and non-experts by capturing how gene drive/genetic biocontrol technologies and issues around the technologies are being represented, discussed, debated and evaluated by the public.


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The state of regulatory and governance frameworks for gene drives outside of Africa

Tags: Africa, Gene drive, Governance, Policy
African Genetic Biocontrol Consortium,  YouTube,  2025.
Regional and global perspectives on gene drive regulation. Discussion on the state of regulatory and governance frameworks for gene drives outside of Africa, covering regional priorities and challenges.

Global and regional updates on gene drive governance; AUDA-NEPAD update on regional work

Tags: Africa, Governance, Policy, Synthetic biology, Video
African Genetic Biocontrol Consortium,  YouTube,  2025.
AUDA-NEPAD update on regional work. Presentation on AUDA-NEPAD’s initiatives and progress in governance and capacity-building efforts related to synthetic biology, particularly on gene drives.

Inside the lab breeding malaria resistant GM mosquitoes

Tags: Gene drive, Malaria, Video
Reuters,  YouTube,  2025.
An international team of scientists are developing genetically modified mosquitoes that can slowly convert the entire wild population of mosquitoes resistant to transmitting malaria, the world’s most deadly disease.

What Is Gene Drive? – Biology For Everyone

Tags: Gene drive, Video
Biology for Everyone,  YouTube,  2025.
What Is Gene Drive? In this informative video, we will introduce you to the intriguing concept of gene drive, a revolutionary technology that enables the rapid transmission of specific traits within a species. We will break down the mechanics of how gene drive works, including ...

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Gene Drive in the News

Gene Drive Technology in the News

This is a collection of articles compiled from lay news sources, including newspapers, newscasts, blogs, and other non-academic communications. This content illustrates how genetic biocontrol and gene drive technologies are described in popular media.


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Unlocking Gene Drive in Agriculture

Tags: Agriculture, Gene drive, Genetic engineering
Sarah Lee,  Number Analytics,  2025.
Gene drive is a revolutionary genetic engineering technique that has the potential to transform the field of agricultural biotechnology. In this section, we will explore the definition, mechanism, and history of gene drive technology, as well as its potential applications in ...

The Future of Gene Drive in Farming

Tags: Agriculture, Ecology, Gene drive
Sarah Lee,  Number Analytics,  2025.
The advent of gene drive technology has opened up new avenues for transforming farming practices, improving crop yields, and promoting sustainability. Gene drive is a genetic engineering technique that allows for the rapid spread of a particular gene or trait through a ...

We finally may be able to rid the world of mosquitoes. But should we?

Tags: Ethics, Gene drive, Mosquitoes
Dino Grandoni,  Wall Street Journal,  2025.
They buzz, they bite, and they cause some of the deadliest diseases known to humanity. Mosquitoes are perhaps the planet’s most universally reviled animals. If we could zap them off the face of the Earth, should we? The question is no longer hypothetical. In recent years, ...

Should we wipe out the pests now that we can?

Tags: Ethics, Pest management
Miguel Ángel Criado,  El Pais,  2025.
Felicola (Lorisicola) isidoroi is a creature that is probably either extinct or on the verge of being so. In the past, it must have been present throughout most of the Iberian Peninsula, but the last time scientists encountered one was in 1997. For biologists, this represents a ...

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Keywords

Aedes Africa Agriculture Anopheles Arbovirus Asia Biodiversity/Conservation Biological control Birds Chromosomal drive Containment CRISPR Culex Cytoplasmic incompatibility Dengue Ecology Ethics Europe Evolution Field trials Fish Fruit fly Gene drive Gene drive mechanisms Gene drive synthetic Gene editing Genetically modified mosquitoes Genetically modified organisms Genetic biocontrol Genetic engineering Genetic incompatibilities Genetics Genomics Governance History Incompatible insect technique Invasive species Malaria Modeling Mosquitoes Mosquito husbandry Moths North America Oceania Other arthropods Other invertebrates Other mammals Other Symbionts Oxitec Pest management Policy Population genetics/dynamics Population modification/replacement Population suppression Regulation Replicator/site directed nuclease Resistance Risk and safety Risk assessment Rodents Selfish genetic elements Self limiting Self sustaining Sex distorter South/Central America South Africa Stakeholder engagement Sterile insect technique (SIT) Synthetic biology Target malaria Toxin-antidote Transmission distortion Underdominance Vector control Video Webinar Wolbachia X chromosome Y-chromosome Yeast and Fungi
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