Video

Daisy-chain gene drives

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MIT Media Lab,  2019-04-03 18:36:17.
Who should decide whether, when, and how to alter the environment? These are hard questions, especially when the decisions will impact people in many different communities or nations. Daisy drive systems may help by empowering local communities to make decisions concerning their local environments without imposing them on anyone else.

A Question of Consent: Exterminator Mosquitoes in Burkina Faso

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ETC group,  2019-01-08 20:10:07.
Target Malaria’s planned release of GMO mosquitos is step toward release of gene drive mosquitoes, a high-risk technology aimed at the elimination of entire species. Hundreds of organizations have demanded a moratorium on the use of this technology outside of strictly-controlled laboratories.

Why I study the most dangerous animal on earth — mosquitoes | Fredros Okumu

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TED,  2018-12-13 16:30:22.
This is a TED talk by an African scientist who reflects on the impact of malaria on Africans and efforts to eliminate the diseases and the need for continued efforts.

Population Engineering | Gene Drive by CRISPR-CAS9

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SciToons,  2018-12-10 18:19:26.
The CRISPR-CAS9 genome editing technology is opening up previously inconceivable possibilities for the manipulation of organisms. Our ethical discussion appears to be far behind the pace of technological development. In this new SciToons video, we address how CRISPR-CAS9 can be used to change entire species using the concept of Gene Drive.

CRISPR Gene Drive (Complete guide 2019)

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Every Cell A Universe,  2018-11-18 18:59:09.
Crispr gene drive - malaria cure and a new way to look at conservation.

Gene drives could wipe out mosquitoes

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New Scientist,  2018-09-25 19:10:14.
This is a short video describing how gene drive is being considered for controlling malaria transmitting mosquitoes in Africa as part of ongoing malaria eradication efforts.

Ethics of sculpting evolution

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K. Esvelt,  PopTech,  2018-09-04 21:34:19.
How might supervillains take over the world, and what can we do about it? Kevin Esvelt, the first to identify the potential for CRISPR “gene drive” systems to alter entire populations of organisms, is calling for a new scientific method that is both open and gives beneficiaries a say in the process.

CRISPR Explained

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Mayo Clinic,  2018-07-24 17:25:24.
A short video that simply explains what CRISPR is and how it is used for gene editing. Simple language and highly accessible.

Gene Editing: Last Week Tonight with John Oliver (HBO)

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J. Oliver,  HBO,  2018-07-01 20:40:49.
Scientists are developing new ways to alter the genetic code of living organisms. John Oliver explores the risks, rewards, and wolf-related hazards of gene editing.

Gene Drives – Wundermittel? Biowaffe?

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Swiss Academy of Sciences,  2018-02-19 21:02:40.
Gene drives are genetic elements that skew the pattern of inheritance of a given characteristic in sexually reproduc- ing organisms. They can be used to spread a characteristic that can alter or even reduce the numbers of individuals in wild populations of a certain species.

Can We Engineer Social Ecosystems?

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Kevin Esvelt,  TEDxCambridgeSalon,  2018-01-19 17:11:31.
Kevin Esvelt is director of the Sculpting Evolution group, which invents new ways to study and influence the evolution of ecosystems. By carefully developing and testing these methods with openness and humility, the group seeks to address difficult ecological problems for the benefit of humanity and the natural world. Prior to joining the MIT Media Lab, Esvelt wove many different areas of science into novel approaches to ecological engineering.

Open, Local, and Obligated

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Yale University,  2017-12-13 17:04:29.
Kevin Esvelt, PhD, assistant professor at the MIT Media Lab and leader of the Sculpting Evolution Group talks about the need for new scientific structures based on transparency and open. This lecture was given at the 2017 Editing Nature Summit.

How selfish DNA hijacks its way into egg cells

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Science,  2017-11-06 13:52:33.
This video was produced by Science magazine and explains and illustrates how gonotaxis or the asymmetrical allocation of chromosomes to developing female gametes occurs in mice. This video reflects an understanding of this process based on the publication by Akera et al (2017).

A secret weapon against Zika and other mosquito-borne diseases

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Nina Federoff,  TEDxMidAtlantic,  2017-07-15 15:37:47.
Where did Zika come from, and what can we do about it? Molecular biologist Nina Fedoroff takes us around the world to understand Zika's origins and how it spread, proposing a controversial way to stop the virus -- and other deadly diseases -- by preventing infected mosquitoes from multiplying.

CRISPR’s Gene Drive Could Revive Extinct Species–or Create New Ones | Jennifer Doudna

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Jennifer Doudna,  Big Think,  2017-06-26 19:28:41.
A leading gene editing scientist, Jennifer Doudna, discusses gene drive and their applications as well as de-extinction technologies.

Area-wide Integrated Pest Management

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Food and Agriculture Organization of the United Nations (FAO),  International Atomic Energy Agency,  2017-05-22 13:34:46.
Throughout history, people have had to fight insect pests to reduce diseases, minimize food losses, protect agricultural trade or simply to avoid the nuisance of stinging, biting and buzzing bugs. Insect pest control is usually implemented locally in individual fields or properties. These uncoordinated efforts often prove inefficient since they only suppress a proportion of the targeted pest population. Pests from nearby untreated areas remain unscathed and can re-enter the treated areas, the damage continues, and people have little choice but to apply the control measures again and again to protect their livelihoods. Area-wide pest management provides a more cost-effective and sustainable approach by proactively targeting entire pest populations. In this way, pest populations can be contained at low levels for longer periods and pest management methods can be integrated that are less reliant on pesticides and that better address ecological and environmental concerns.

Gene drive for Malaria control | Andrea Crisanti |

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TEDx,  2017-04-04 19:23:37.
Andrea discusses his team's laboratory work that has developed a revolutionary technology to spread genetic modifications from few laboratory mosquitoes to wild populations to eradicate malaria in the near future

Genetic Engineering and Diseases – Gene Drive & Malaria

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Kurzgesagt – In a Nutshell,  2016-09-21 00:00:00.
This video focuses on the basic applications of gene drive to malaria eradication and leave the viewer with the question “what do you think?”

Gene Drives: Saving Lives Or Powering Extinctions?

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Fw:Thinking,  2016-07-06 18:25:32.
A few months back we talked about the revolutionary gene-editing technique known as CRISPR-Cas9 – a technology based on the bacterial immune system that will allow us to make edits to an organism’s genetic code with more ease and accuracy than ever before. CRISPR is changing the landscape of genetic engineering and synthetic biology. In this episode, we take a look at one of the most powerful applications in this new landscape of genetic engineering: Gene drives. This is an idea that has the potential to save millions of lives and give us unprecedented control over natural populations of organisms. At the same time, it comes with serious risks that need to be studied and understood. Should we use gene drives at all? If so, what should we use them for? And what safety measures should we put in place?

Openly Engineering Our Ecosystems

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TEDxCambridge,  2016-06-22 18:00:37.
Which technologies should we develop and how? Kevin Esvelt, leader of the Sculpting Evolution group and a professor at the MIT Media Lab, describes how CRISPR 'gene drives' can single-handedly alter entire wild populations and the critical importance of requiring powerful technologies to be developed in the open light of day.

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