Yan & Finnigan, (2018) recently published a paper in Scientific Reports describing an artificial multi-locus gene drive system by using a single Cas9 and three guide RNA (gRNA) in the budding yeast Saccharomyces cerevisiae. Nuclease-based gene drives do not follow the typical Mendel patterns of inheritance and lead quickly to the spread of gene drive elements through a given population.
https://www.geneconvenevi.org/wp-content/uploads/2018/09/IGTRCN.png300300Academic Web Pages/wp-content/uploads/2019/10/GC-color-logo-for-header-3277-x-827-1030x260.pngAcademic Web Pages2019-01-14 00:00:002020-04-28 14:26:40A Multiple Gene Drive System