Cas9 Gene Drive, Sex-Conversion and Evolved Resistance
Cas9 Gene Drive, Sex-Conversion and Evolved Resistance
Tags: CRISPR, Fruit flyAnna Buchman, IGTRCN, 2018.
In a recent manuscript, KaramiNejadRanjbar et al. demonstrate the development of a proof of principle Cas9-based suppression gene drive in D. melanogaster that can be applied to pest insects, and discuss the implications of resistance allele formation for practical use of such a drive system.