Could editing the genomes of bats prevent future coronavirus pandemics? Two scientists think it’s worth a try

E. C. Hayden,  STAT,  2021.

Amid the devastating Covid-19 pandemic, two researchers are proposing a drastic way to stop future pandemics: using a technology called a gene drive to rewrite the DNA of bats to prevent them from becoming infected with coronaviruses. The scientists aim to block spillover events, in which viruses jump from infected bats to humans — one suspected source of the coronavirus that causes Covid. Spillover events are thought to have sparked other coronavirus outbreaks as well, including SARS-1 in the early 2000s and Middle East respiratory syndrome (MERS). This appears to be the first time that scientists have proposed using the still-nascent gene drive technology to stop outbreaks by rendering bats immune to coronaviruses, though other teams are investigating its use to stop mosquitoes and mice from spreading malaria and Lyme disease.

 


More related to this:

Designing gene drives to limit spillover to non-target populations

Engineering speciation events in insects may be used to control harmful pests

Transcontinental dispersal of Anopheles gambiae occurred from West African origin via serial founder events

Gene Drives across engineered fitness valleys: Modeling a design to prevent drive spillover.

3 innovative technologies stopping malaria