Keywords: gene drive synthetic

FNIH Panel on Gene Drive Regulation Emphasizes Need for Local Community Engagement

C. Rizk,  GenomeWeb,  2020.
Genetically modified organisms are another topic of deep debate, with some activists agitating for and getting governments to implement deep restrictions on modified crops. More recently, GMO crops have started to regain public favor, particularly in countries where boosting the ...
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‘A plague to be reckoned with’: UMN research creates a buzz with invasive fruit fly research

B. Most,  The Minnesota Daily,  2020.
n early November, assistant professor Mike Smanski published an article about a new breakthrough in this research, demonstrating for the first time this kind of genetic engineering was possible in the common fruit fly. This shows that researchers could engineer this work into ...
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Standardizing the Definition of Gene Drive

L. S. Alphey, A. Crisanti, F. Randazzo and O. S. Akbari,  Proceedings of the National Academy of Sciences,  202020417. 2020.
As members of the gene drive community, we have developed a set of definitions to help stakeholders discuss the topic and communicate using a common understanding of terms.
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The promise of CRISPR and gene drive systems to end malaria in Africa

E. Gomez-Diaz,  ARRIGE ORG,  2020.
Presentation by Elena Gómez Díaz (IPBLN-CSIC, Granada, Spain) at the ARRIGE 2020 meeting on "The promise of CRISPR and gene drive systems to end malaria in Africa". Discussion is included at the end of the Ruud de Maagd presentation.https://youtu.be/te3MJ8EZoes
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Further guidance required for assessment of gene drive technology, says EFSA

N. Foote,  Euractiv,  2020.
After being mandated by the European Commission, EFSA’s experts on genetically modified organisms (GMOs) published the scientific opinion related to engineered gene drives on Thursday (12 November), specifically focusing on gene drive modified disease-transmitting insects, ...
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Further guidance required for assessment of gene drive technology, says EFSA

Euractiv,  The World News Monitor,  2020.
Existing guidelines are adequate for evaluating risks associated with gene-drive modified insects, but further guidance is needed for some areas, most notably for environmental risk assessments. The evaluation was requested to explore the issue ahead of the consideration of any ...
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Mutagenic chain reaction cannot be sufficiently controlled

Christoph Then,  Testbiotech,  2020.
The European Food Safety Authority (EFSA) has published the results of its public consultation on the risks of so-called gene drive organisms. Testbiotech accuses the authority of disguising the real dimension of the risks. Gene drives are designed to spread artificial genetic ...
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Adequacy and sufficiency evaluation of existing EFSA guidelines for the molecular characterisation, environmental risk assessment and post-market environmental monitoring of genetically modified insects containing engineered gene drives

E. Panel o. G. M. Organisms, H. Naegeli, J.-L. Bresson, T. Dalmay, I. C. Dewhurst, M. M. Epstein, P. Guerche, J. Hejatko, F. J. Moreno, E. Mullins, F. Nogué, N. Rostoks, J. J. Sánchez Serrano, G. Savoini, E. Veromann, F. Veronesi, M. B. Bonsall, J. Mumfor,  EFSA Journal,  18:e06297. 2020.
As a proactive measure, the European Food Safety Authority (EFSA) has been requested by the European Commission to review whether its previously published guidelines for the risk assessment of genetically modified animals (EFSA, 2012 and 2013), including insects (GMIs), are ...
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Outcome of a public consultation on the draft adequacy and sufficiency evaluation of existing EFSA guidelines for the molecular characterisation, environmental risk assessment and post-market environmental monitoring of genetically modified insects containing engineered gene drives

European Food Safety Authority, Y. Devos, M. B. Bonsall, F. Nogué, K. Paraskevopoulos, E. A. Wimmer and L. G. Firbank,  EFSA Supporting Publications,  17:1939E. 2020.
The European Food Safety Authority (EFSA) carried out an online public consultation to receive input from interested parties/persons on the draftscientific opinion on the adequacy and sufficiencyevaluation of existing guidelines for the molecular characterisation (MC), ...
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EFSA advises on risk assessment of engineered gene drives

EFSA,  European Food and Safety Authority,  2020.
EFSA’s existing guidelines for the risk assessment of genetically modified animals are adequate for evaluating risks associated with gene drive modified insects. However, further guidance is needed for some areas, such as molecular characterisation, environmental risk ...
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Gene drives, species, and compassion for individuals in conservation biology

Y. Rohwer,  Ethics, Policy and Environment,  2020.
In this paper I argue that these compassionate conservationists have a moral obligation to support the investigation and development of genetic modification technologies because of their potential to minimize suffering and eliminate killing in conservation. Furthermore, I will ...
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Novel and Exceptional Technology and Research Advisory Committee – NExTRAC -NIH

NIH Office of Science Policy,  National Institutes of Health (NIH),  2020.
NExTRAC provides advice to the Director of the National Institutes of Health (NIH) on matters related to the conduct and oversight of research involving emerging technologies in biomedical science. NExTRAC also makes recommendations on research involving the use of, and ...
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When Extinction is Warranted: Invasive Species, Suppression-Drives, and the Worst-Case Scenario

A. C. Thresher,  Ethics, Policy and Environment,  2020.
The focus of this paper is on one such risk ? the danger of a suppression-drive escaping containment and wiping out the target species globally. Here, I argue that in most cases this risk is significant enough to warrant holding off on the technology. In some cases, however, we ...
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Brave New Planet: Reshaping Nature Through Gene Drives

E. Lander,  Brave New Planet,  2020.
A new technology, called gene drives, has the power to spread any genetic instructions you wish across an entire animal or plant species in the wild. It might let us restore ecosystems ravaged by invasive species, or help species adapt to climate change. And, it might save ...
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Gene drive blocks malaria transmission in mosquitoes

labonline,  labonline,  2020.
Employing a strategy known as ‘population modification’, which involves using a CRISPR-Cas9 gene drive system to introduce genes preventing parasite transmission into mosquito chromosomes, University of California (UC) researchers have made a major advance in the use of ...
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The ethical way to alter organisms

K. Esvelt,  Boston Globe,  2020.
As my colleagues and I first described in 2014, we can use CRISPR genome editing to duplicate the most powerful form of “gene drive,” a ubiquitous natural phenomenon that happens when a genetic change is inherited more frequently than usual. Encode the CRISPR machinery next ...
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Gene Drives: A Controversial Tool to Fight Malaria

H. Albert,  LABIOTECH.eu,  2020.
The possibility of creating gene drives was introduced into the scientific community in 2003 by Austin Burt, a professor at Imperial College London. Burt was studying ‘selfish genes’ that can copy themselves into a specific target DNA sequence. He suggested that these genes, ...
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Expert advises farmers to adopt gene drive-based pest control technology

S. Thompson,  naija247news,  2020.
Dr Rose Gidado, County Coordinator, Open Forum on Agricultural Biotechnology(OFAB), has advised farmers to adopt the gene drive-based pest control technology. Gidado, also Deputy Director, National Biotechnology Development Agency (NABDA), said the adoption would significantly ...
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Research and Innovation for biodiversity: what role for gene drive research?

EP Intergroup CCBSD,  European Bureau of Conservation and Development,  2020.