Gene drives to fight malaria: current state and future directions
/in
Hammond, A. M. and R. Galizi,
Pathogens and Global Health,
111:412-423.
2017.
Self-propagating gene drive technologies have a number of desirable characteristics that warrant their development for the control of insect pest and vector populations, such as the malaria-transmitting mosquitoes. Theoretically easy to deploy and self-sustaining, these tools may be used to generate cost-effective interventions that benefit society without obvious bias related to wealth, age or education. Their species-specific design offers the potential to reduce environmental risks and aim to be compatible and complementary with other control strategies, potentially expediting the elimination and eradication of malaria. A number of strategies have been proposed for gene-drive based control of the malaria mosquito and recent demonstrations have shown proof-of-principle in the laboratory. Though several technical, ethical and regulatory challenges remain, none appear insurmountable if research continues in a step-wise and open manner.
https://www.geneconvenevi.org/wp-content/uploads/2020/04/Pathogens-and-Global-Health-3.png300300David Obrochta/wp-content/uploads/2019/10/GC-color-logo-for-header-3277-x-827-1030x260.pngDavid Obrochta2017-12-17 15:55:062020-04-22 16:54:06Gene drives to fight malaria: current state and future directions