Haldane’s duel: intragenomic conflict, selfish Y chromosomes and speciation

Haldane’s duel: intragenomic conflict, selfish Y chromosomes and speciation

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S. W. Roy,  Trends in Genetics,  2021-06-21 14:14:05.

Haldane’s rule, which states that the heterogametic sex (XY or ZW females) fares more poorly in interspecific hybrids, is generally attributed to absence of one of the two species’ X/Z chromosomes. However, Haldane?s rule is also observed in mouse placentas despite paternal X silencing. This pattern could reflect Y chromosomes having evolved to promote growth due to maternal?paternal conflict. If so, balanced sex investment arises from a complex intra- and intergenomic duel.