Meiotic drive in Lucilia cuprina and chromosomal evolution

In females heterozygous for pericentric inversions that alter the relative lengths of the long and short arms of a chromosome, crossing-over within the inversion can lead to unequal segregation at anaphase II, favoring the homologue with the more centrally located centromere. It is suggested that this phenomenon may have played a role in the evolution of centromere position in certain species groups.