Scholarly Literature

This is a database of scholarly literature that concentrates currently on natural and engineered selfish genetic elements (gene drives).  The latest are shown here.
Disclaimer>

Meiotic defects in human oocytes: Potential causes and clinical implications

Tags: , ,
T. Wu, H. Gu, Y. Luo, L. Wang and Q. Sang,  BioEssays,  2022.
Meiotic defects cause abnormal chromosome segregation leading to aneuploidy in mammalian oocytes. Chromosome segregation is particularly error-prone in human oocytes, but the mechanisms behind such errors remain unclear. To explain the frequent chromosome segregation errors, ...

Wolbachia-Virus interactions and arbovirus control through population replacement in mosquitoes

Tags: , , , ,
T. H. Ant, M. V. Mancini, C. J. McNamara, S. M. Rainey and S. P. Sinkins,  Pathogens and Global Health,  2022.
Following transfer into the primary arbovirus vector Aedes aegypti, several strains of the intracellular bacterium Wolbachia have been shown to inhibit the transmission of dengue, Zika, and chikungunya viruses, important human pathogens that cause significant morbidity and ...

Fitness costs of Wolbachia shift in locally-adapted Aedes aegypti mosquitoes

Tags: , , , ,
P. A. Ross and A. A. Hoffmann,  Environmental Microbiology,  2022.
Aedes aegypti mosquito eggs can remain quiescent for many months before hatching, allowing populations to persist through unfavorable conditions. Aedes aegypti infected with the Wolbachia strain wMel have been released in tropical and subtropical regions for dengue control. wMel ...

Mitotic exchange in female germline stem cells is the major source of Sex Ratio chromosome recombination in Drosophila pseudoobscura

Tags: , , , ,
S. Koury,  G3 Genes|Genomes|Genetics,  2022.
Sex Ratio chromosomes in Drosophila pseudoobscura are selfish X chromosome variants associated with three non-overlapping inversions. In the male germline, Sex Ratio chromosomes distort segregation of X and Y chromosomes (99:1), thereby skewing progeny sex ratio. In the female ...

Aedes albopictus Sterile Male Production: Influence of Strains, Larval Diet and Mechanical Sexing Tools

M. Malfacini, A. Puggioli, F. Balestrino, M. Carrieri, M. L. Dindo and R. Bellini,  Insects,  2022.
The sterile insect technique (SIT) is a biologically based method of pest control, which relies on the mass production, sterilization, and release of sterile males of the target species. Since females can transmit viruses, it is important to develop a mass rearing system to ...

Justifying an Intentional Species Extinction: The Case of Anopheles gambiae

Tags: , , , , , ,
D. E. Callies and Y. Rohwer,  Environmental Values,  31:193-210. 2022.
Each year, over 200 million people are infected with the malaria parasite, nearly half a million of whom succumb to the disease. Emerging genetic technologies could, in theory, eliminate the burden of malaria throughout the world by intentionally eradicating the mosquitoes that ...

Distribution of sex ratio distorters in natural populations of the isopod Armadillidium vulgare

Tags: ,
2022.

Externalities modulate the effectiveness of the Wolbachia release programme

Tags: , , , , ,
E. E. Ooi and A. Wilder-Smith,  The Lancet Infectious Diseases,  2022.
Despite the remarkable outcome in Yogyakarta, the wMel approach also has some challenges. In particular, the extent to which ecological, weather, and other external factors influence the dissemination and establishment of wMel in complex urban environments remains unclear. ...

Estimating the effect of the wMel release programme on the incidence of dengue and chikungunya in Rio de Janeiro, Brazil: a spatiotemporal modelling study

Tags: , , , , ,
G. Ribeiro dos Santos, B. Durovni, V. Saraceni, T. I. Souza Riback, S. B. Pinto, K. L. Anders, et al.,  The Lancet Infectious Diseases,  2022.
Summary Background Introgression of genetic material from species of the insect bacteria Wolbachia into populations of Aedes aegypti mosquitoes has been shown in randomised and non-randomised trials to reduce the incidence of dengue; however, evidence for the real-world ...

The Involvement of Atlastin in Dengue Virus and Wolbachia Infection in Aedes aegypti and Its Regulation by aae-miR-989

Tags: , ,
M. Hussain, T. Bradshaw, M. Lee and S. Asgari,  Microbiology Spectrum,  2022.
Endoplasmic reticulum (ER)-shaping atlastin proteins (ATLs) have been demonstrated to play a functional role during flavivirus replication in mammalian cells. For dengue virus (DENV), atlastin is required in the formation of the replication organelles and RNA replication, virion ...

Wolbachia action in the sperm produces developmentally deferred chromosome segregation defects during the Drosophila mid-blastula transition

Tags: , ,
B. Warecki, S. W. A. Titen, M. S. Alam, G. Vega, N. Lemseffer, K. Hug, et al.,  eLife,  11:e81292. 2022.
Wolbachia, a vertically transmitted endosymbiont infecting many insects, spreads rapidly through uninfected populations by a mechanism known as cytoplasmic incompatibility (CI). In CI, a paternally delivered modification of the sperm leads to chromatin defects and lethality ...

Meiotic drive is associated with sexual incompatibility in Neurospora

Tags: ,
A. Vogan, J. Svedberg, M. Grudzinska-Sterno and H. Johannesson,  Evolution,  2022.
Evolution of Bateson-Dobzhansky-Muller (BDM) incompatibilities is thought to represent a key step in the formation of separate species. They are incompatible alleles that have evolved in separate populations and are exposed in hybrid offspring as hybrid sterility or lethality. In ...

Fitness effects of CRISPR endonucleases in Drosophila melanogaster populations

Tags: , , , ,
A. M. Langmüller, J. Champer, S. Lapinska, L. Xie, M. Metzloff, S. E. Champer, J. Liu, Y. Xu, J. Du, A. G. Clark and P. W. Messer,  eLife,  11:e71809. 2022.
Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR)/Cas9 provides a highly efficient and flexible genome editing technology with numerous potential applications ranging from gene therapy to population control. Some proposed applications involve the integration of ...

Wolbachia strain wAlbB remains stable in Aedes aegypti over 15 years but exhibits genetic background-dependent variation in virus blocking

Tags: , , ,
X. Liang, C. H. Tan, Q. Sun, M. Zhang, P. J. Wong, M. I. Li, et al.,  PNAS Nexus,  2022.
The ability of the maternally transmitted endosymbiotic bacterium Wolbachia to induce cytoplasmic incompatibility (CI) and virus blocking makes it a promising weapon for combatting mosquito-borne diseases through either suppression or replacement of wild-type populations. Recent ...

Daisy-chain gene drives: The role of low cut-rate, resistance mutations, and maternal deposition

Tags: , , ,
S. A. N. Verkuijl, M. A. E. Anderson, L. Alphey and M. B. Bonsall,  PLOS Genetics,  18:e1010370. 2022.
Author summary Reducing the harm of pest species by the introgression of traits into a wild population is often limited by the difficulties of mass rearing and release of modified individuals. Gene drives present an opportunity to substantially reduce the release frequencies ...

Genome sequencing and comparative analysis of Wolbachia strain wAlbA reveals Wolbachia-associated plasmids are common

Tags:
J. Martinez, T. H. Ant, S. M. Murdochy, L. Tong, A. da Silva Filipe and S. P. Sinkins,  PLOS Genetics,  18:e1010406. 2022.
Wolbachia is the most common bacterial symbiont of arthropods, being found in about half of terrestrial species around the globe. It is transmitted from mother to offspring, can spread rapidly by inducing various forms of reproductive parasitism and often provides protection ...

Meiotic drive does not impede success in sperm competition in the stalk-eyed fly, Teleopsis dalmanni

Tags: ,
S. Bates, L. Meade and A. Pomiankowski,  bioRxiv,  2022.
Meiotic drive genes are selfish genetic elements that distort Mendelian patterns of inheritance to bias transmission in their favour. We use the stalk-eyed fly, Teleopsis dalmanni, to investigate the fitness effects associated with a meiotic drive gene called Sex Ratio (SR), ...

Enforcement of Postzygotic Species Boundaries in the Fungal Kingdom

Tags: ,
J. Y. Chou, P. C. Hsu and J. Y. Leu,  Microbiology and Molecular Biology Reviews,  2022.
Understanding the molecular basis of speciation is a primary goal in evolutionary biology. The formation of the postzygotic reproductive isolation that causes hybrid dysfunction, thereby reducing gene flow between diverging populations, is crucial for speciation. Using various ...

Quality control traceability during the packing and release process of Ceratitis capitata for sterile insect technique

Tags: ,
Y. Contreras-Navarro, H. Luis-Alvarez, G. García-Coapio, R. Hernández, S. Flores and P. Montoya,  Journal of Applied Entomology,  2022.
Abstract In programmes applying the sterile insect technique (SIT), the quality of insects deployed in the field determines the success in preventing, suppressing, containing or eradicating the pest population. In the fruit fly emergence and release facility (ERF) of the Moscamed ...

Transposable elements

A. Hayward and C. Gilbert,  Current Biology,  32:R904-r909. 2022.
Transposable elements are known by many names, including 'transposons', 'interspersed repeats', 'selfish genetic elements', 'jumping genes', and 'parasitic DNA', but here we will refer to them simply as transposable elements. Many biologists will have heard of transposable ...

« First ‹ Previous 1 26 34 35 36 37 38 46 118 Next › Last »