Video

Genetically modified mosquitoes could combat deadly diseases, scientists say

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The Sydney Morning Herald,  2025-01-13 15:25:27.
Genetically modified mosquitoes could be the solution to stopping deadly diseases spread by mosquito bites, scientists say.

Why are gene drive technologies being considered to help restore biodiversity on islands?

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Outreach Network for Gene Drive Research,  2024-10-15 11:55:45.
Researchers have been studying how to harness gene drives to solve some of society’s most intractable problems for a long time. Public health and ecosystem conservation are two of the main areas where research has focused, although other uses are also possible.

Gene Drives: A Powerful and Controversial Genetic Technology

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Biomedical and Life Sciences Simplified,  YouTube,  2024-09-03 09:01:56.
Gene drives represent a powerful yet controversial genetic technique that challenges traditional Mendelian inheritance. By introducing self-propagating changes into an organism's genome, gene drives can ensure that a specific mutation becomes homozygous in offspring, effectively spreading it through a population. This powerful tool has potential applications in eradicating mosquito-borne diseases like malaria and Zika, combating drug-resistant pathogens, and controlling invasive species. But how exactly does it work? This video breaks down the science behind gene drives and the role of CRISPR technology.

World Mosquito Day: Gene Drives and CRISPR Technology

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Public Health On Call,  YouTube,  2024-08-27 14:16:24.
About this episode: World Mosquito Day, observed annually on August 20th, commemorates British doctor Sir Ronald Ross's discovery in 1897 that female Anopheles mosquitoes transmit malaria to humans. More than a century later, major advancements like genetically modifying mosquitoes—AKA gene drives—have the potential to reduce malaria cases and deaths dramatically, but not without hurdles. This special episode is an extended version of Malaria Minute, a podcast from the Johns Hopkins Malaria Research Institute.

Djibouti Unleashes Controversial Genetically Modified Mosquitoes

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Palki Sharma,  Firstpost,  2024-06-04 20:55:28.
Djibouti is combatting malaria by employing a unique tactic: utilising mosquitoes to battle mosquitoes. The East African nation has released tens of thousands of genetically engineered mosquitoes armed with a "self-limiting" gene. This bioengineered gene aims to curb mosquito populations by terminating their offspring. However, concerns have been voiced about the experimental nature of this genetic modification technique and the absence of adequate regulation. While Burkina Faso, Brazil, Panama, and India have ventured into similar endeavors, the efficacy and long-term implications of such interventions remain uncertain. The debate persists: are genetically modified mosquitoes a daring gamble or a promising solution to eradicate deadly diseases like malaria?

How to Use Genetic Biocontrol to Manage Insect Pests

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Scientific Animations Without Borders,  YouTube,  2024-05-07 16:41:35.
Pest insects often transmit disease to humans and animals and destroy crops. Controlling these pests can improve human health and increase agricultural production. Pest insects are often controlled by releasing other insects into the environment that will specifically kill the pests. This method of pest control is called biological control and is environmentally friendly because it reduces reliance on chemical insecticides and targets only the pest insects. Genetic biocontrol is a type of biological control where the released insects are the same species as the pest but with critical genetic differences and traits that affect their reproduction or lifespan.

High-Stakes Decision Making for World-Changing Technologies

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TEDx Talks,  YouTube,  2024-04-02 19:48:16.
We have important decisions to make that require rigorous and inclusive decision-making models that can be applied on a broad scale to a growing number of emerging challenges.

Flight Against Infections: The Role of Genetically Engineered Mosquitoes, with Dr. Stephanie James

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EeKs on Health,  YouTube,  2024-03-11 10:40:20.
In this episode of Causes or Cures, Dr. Eeks chats with Dr. Stephanie James about the potential use of genetically modified mosquitoes (GMMs) to fight diseases that mosquitoes carry and spread, such as Malaria and Dengue Fever. In the podcast, Dr. James provides an overview on GMMs, as well as what something called Gene Drive Modified Mosquitoes (GDMMs) are. She talks about the current state of research, testing, and describes the GeneConvene Global Collaborative "GeneConvene", which was created to advance best practices and informed decision making for developing GMMs and GDMMs. She talks about the potential benefits versus the potential risks, how they are conducting risk assessments, how they plan to test GMMs, the ethical and safety concerns, and how local communities will be included in the decision-making process.

Mosquito Control releases over 100K sterile male mosquitos to combat Aedes aegypti population

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NBC2 News,  2024-03-05 14:41:50.
Mosquito Control releases over 100K sterile male mosquitos to combat Aedes aegypti population

“Mozzie Drive” Card Game rules

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Katie Willis, Ace North,  Target Malaria,  2024-02-27 18:24:27.
Mozzie Drive is an educational card game that demonstrates how gene drive technology could be used to reduce populations of malaria mosquitoes. To download the game for free, please visit: https://targetmalaria.org/why-malaria... . This game was designed by Dr. Katie Willis and Dr. Ace North from the Target Malaria modelling team.

SPOTLIGHT: Gene Drives for Malaria Elimination in Africa

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Ifakara Health Institute,  YouTube,  2024-02-20 20:05:51.
This SPOTLIGHT Series features Dr. Marceline Finda, a distinguished Research Scientist at Ifakara Health Institute. The insightful 20-minute discussion centered around the topic: "Gene Drives for Malaria Elimination in Africa."

Scientists create first transgenic mosquito strain in Africa

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CGTN Africa,  2024-01-28 13:15:53.
Scientists in Tanzania have created the first transgenic mosquito strain in Africa. This genetically modified strain aims to prevent malaria transmission.

Gene Drives: Mechanisms and Key Research, Explained

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Julia Bauman,  60 Second Science,  2024-01-15 16:59:40.
A technical primer on CRISPR-based gene drives, which hold massive potential for mitigating the harms invoked by some species. We cover what a gene drive is, how it works at the genetic level, and summarize key safety & efficiency features developed in recent years.

Off Target: Gene Drives and the Balance of Life

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Save Our Seeds,  2023-06-28 09:25:43.
This is a compilation of conversations with experts about gene drive technologies and the science/social questions it raises.

Regulation of gene drive technologies for malaria control & elimination

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Ifakara Health Institute,  2023-05-16 13:15:08.
The video talks about the importance of ensuring effective and thoughtful community and stakeholder engagement throughout research, development and deployment of gene drives for malaria control.

Ethical dilemma: Should we get rid of mosquitoes?

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Talya Hackett,  TED-Ed,  2023-01-30 09:59:15.
Mosquitoes are responsible for more human deaths every year than any other animal, but very few of the 3,500 mosquito species actually transmit deadly diseases to humans. Scientists have been conducting experiments using engineered technologies called gene drives that could theoretically get rid of the most lethal mosquitoes. So, should we eradicate these pesky insects? Talya Hackett investigates.

Discovery of 119-Million year old Selfish Genes Casts Doubt on Established Evolution Beliefs

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Stowers Institute for Medical Research,  2022-11-23 10:39:51.
Meiotic drivers, a kind of selfish gene, are indeed selfish. They are found in virtually all species’ genomes, including humans, and unjustly transfer their genetic material to more than half of their offspring, resulting in infertility and impaired organism health. Their longevity over evolutionary time was thought to be brief due to their parasitic potential, until recently. The Stowers Institute for Medical Research, in collaboration with the National Institute for Biological Sciences in Beijing, China, has discovered a selfish gene family that has survived for over 100 million years—ten times longer than any other meiotic driver ever identified—calling into question established beliefs about how natural selection and evolution deal with these threatening sequences.

Inside the Plan to Release Life-Saving Mosquitoes

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WIRED,  2022-06-10 06:28:48.
The Florida Keys Mosquito Control District is turning towards a novel tool to combat harmful insecticide-resistant mosquitoes like the Aedes aegypti. What are they doing exactly? They're releasing millions of genetically modified male mosquitoes engineered to reduce the population of Aedes aegypti. How exactly does this work? We'll break it down.

In Real Life: GMOsquitoes

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Newsy,  2021-12-06 20:41:41.
The release of genetically modified mosquitoes in Florida gives hope of reducing the spread of disease while causing concerns among some citizens.

Why do you think a gene drive approach could help with malaria and dengue?

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Outreach Network for Gene Drive Research,  2021-04-12 14:42:36.
Why do you think a gene drive approach could help with malaria and dengue? 

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