Mouse t haplotypes are descendents of a variant form of chromosome 17 that evolved the ability to propagate itself at the expense of the wild-type homolog from heterozygous +/t males. Although once enigmatic, these widespread selfish chromosomes have revealed many of their secrets in response to a combined assault with molecular, genetic and phylogenetic techniques. This review summarizes the current understanding of t haplotypes and their raison d’etre.
https://www.geneconvenevi.org/wp-content/uploads/2020/04/Trends-in-Genetics-8.png300300Academic Web Pages/wp-content/uploads/2019/10/GC-color-logo-for-header-3277-x-827-1030x260.pngAcademic Web Pages1993-01-06 00:00:002020-04-22 16:47:41The peculiar journey of a selfish chromosome: Mouse t-haplotypes and meiotic drive