Aedes aegypti microbiome composition covaries with the density of Wolbachia infection

Jane Pascar, Henry Middleton & Steve Dorus,  Microbiome,  11. 2023.

Wolbachia is a widespread bacterial endosymbiont that can inhibit vector competency when stably transinfected into the mosquito, Aedes aegypti, a primary vector of the dengue virus (DENV) and other arboviruses. Although a complete mechanistic understanding of pathogen blocking is lacking, it is likely to involve host immunity induction and resource competition between Wolbachia and DENV, both of which may be impacted by microbiome composition. The potential impact of Wolbachia transinfection on host fitness is also of importance given the widespread release of mosquitos infected with the Drosophila melanogaster strain of Wolbachia (wMel) in wild populations. Here, population-level genomic data from Ae. aegypti was surveyed to establish the relationship between the density of wMel infection and the composition of the host microbiome.

More related to this:

Origin, composition, and structure of the supernumerary B chromosome of Drosophila melanogaster

Engineering the Composition and Fate of Wild Populations with Gene Drive

Satellite DNAs unveil clues about the ancestry and composition of B chromosomes in three grasshopper species

Wolbachia interacts with the microbiome to shape fitness-associated traits during seasonal adaptation in Drosophila melanogaster

Microbiome Innovation in Agriculture: Development of Microbial Based Tools for Insect Pest Management