George, D. R., T. Kuiken and J. A. Delborne,
Proceedings of the Royal Society B: Biological Sciences,
286:20191484..
2019.
Recent statements by United Nations bodies point to free, prior and informed consent (FPIC) as a potential requirement in the development of engineered gene drive applications. As a concept developed in the context of protecting Indigenous rights to self-determination in land development scenarios, FPIC would need to be extended to apply to the context of ecological editing. Without an explicit framework of application, FPIC could be interpreted as a narrowly framed process of community consultation focused on the social implications of technology, and award little formal or advisory power in decision-making to Indigenous peoples and local communities. In this paper, we argue for an articulation of FPIC that attends to issues of transparency, iterative community-scale consent, and shared power through co-development among Indigenous peoples, local communities, researchers and technology developers. In realizing a comprehensive FPIC process, researchers and developers have an opportunity to incorporate enhanced participation and social guidance mechanisms into the design, development and implementation of engineered gene drive applications.
https://www.geneconvenevi.org/wp-content/uploads/2020/04/Proceedings-of-the-Royal-Society-B-1.png300300David Obrochta/wp-content/uploads/2019/10/GC-color-logo-for-header-3277-x-827-1030x260.pngDavid Obrochta2019-12-19 14:30:322020-04-22 16:55:21Articulating ‘free, prior and informed consent’ (FPIC) for engineered gene drives