Scholarly Literature
This is a database of scholarly literature that concentrates currently on natural and engineered selfish genetic elements (gene drives). The latest are shown here.
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Assessing potential hybridization between a hypothetical gene drive-modified Drosophila suzukii and nontarget Drosophila species
Tags: Fruit fly, Gene drive, Gene drive synthetic, Governance, Invasive species, Policy, Risk assessmentS. Wolf, J. Collatz, J. Enkerli, F. Widmer and J. Romeis, Risk Analysis, 2023.
Genetically engineered gene drives (geGD) are potentially powerful tools for suppressing or even eradicating populations of pest insects. Before living geGD insects can be released into the environment, they must pass an environmental risk assessment to ensure that their release ...
Complicated expansion trajectories of insertion sequences and potential association with horizontal transfer of Wolbachia DNA
Tags: Population genetics/dynamics, Selfish genetic elements, WolbachiaY. H. Miao, D. W. Huang and J. H. Xiao, Zoological Research, 44:273-275. 2023.
Insertion sequences (ISs) are the simplest structural transposable elements (TEs) in prokaryotes, consisting only of a transposase coding sequence and its bilateral short terminal inverted repeats. Due to their gradually streamlined genomic construction, TEs rarely exist in the ...
Closing the gap to effective gene drive in Aedes aegypti by exploiting germline regulatory elements
Tags: Aedes, Gene drive, Gene drive synthetic, Genetic biocontrolM. A. E. Anderson, E. Gonzalez, J. X. D. Ang, L. Shackleford, K. Nevard, S. A. N. Verkuijl, M. P. Edgington, T. Harvey-Samuel and L. Alphey, Nature Communications, 14:338. 2023.
CRISPR/Cas9-based homing gene drives have emerged as a potential new approach to mosquito control. While attempts have been made to develop such systems in Aedes aegypti, none have been able to match the high drive efficiency observed in Anopheles species. Here we generate Ae. ...
Both male and female meiosis contribute to non-Mendelian inheritance of parental chromosomes in interspecific plant hybrids (Lolium x Festuca)
Tags: Agriculture, Transmission distortionJ. Majka, M. Glombik, A. Dolezalova, J. Knerova, M. T. M. Ferreira, Z. Zwierzykowski, M. Duchoslav, B. Studer, J. Dolezel, J. Bartos and D. Kopecky, NEW PHYTOLOGIST, 2023.
Some interspecific plant hybrids show unequal transmission of chromosomes from parental genomes to the successive generations. It has been suggested that this is due to a differential behavior of parental chromosomes during meiosis. However, underlying mechanism is unknown. We ...
Joint FAO/IAEA Coordinated Research Project on Mosquito Handling, Transport, Release and Male Trapping Methods in Support of SIT Application to Control Mosquitoes
Tags: Aedes, Genetic biocontrol, Incompatible insect technique, Sterile insect technique (SIT)M. Gómez, B. J. Johnson, H. C. Bossin and R. Argilés-Herrero, Insects, 14. 2023.
The research carried out in the framework of this CRP generated key achievements in areas relevant to the SIT application to control mosquitoes. Among these outcomes, particular mentions must be given to the following: (1) Novel and efficient self-marking techniques were ...
Wolbachia Promotes Its Own Uptake by Host Cells
Tags: Fruit fly, WolbachiaL. B. Nevalainen, E. M. Layton and I. L. G. Newton, Infection and Immunity, e0055722. 2023.
Wolbachia pipientis is an incredibly widespread bacterial symbiont of insects, present in an estimated 25 to 52% of species worldwide. Wolbachia is faithfully maternally transmitted both in a laboratory setting and in the wild. In an established infection, Wolbachia is primarily ...
Wolbachia RNase HI contributes to virus blocking in the mosquito Aedes aegypti
Tags: Aedes, Dengue, Mosquitoes, WolbachiaM. Hussain, G. Zhang, M. Leitner, L. M. Hedges and S. Asgari, iScience, 26:105836. 2023.
The endosymbiotic bacterium Wolbachia pipientis blocks replication of several arboviruses in transinfected Aedes aegypti mosquitoes. However, the mechanism of virus blocking remains poorly understood. Here, we characterized an RNase HI gene from Wolbachia, which is rapidly ...
Engineered symbiotic bacteria interfering Nosema redox system inhibit microsporidia parasitism in honeybees
Tags: Other arthropods, Other SymbiontsH. Lang, H. Wang, H. Wang, X. Xie, X. Hu, X. Zhang and H. Zheng, bioRxiv, 2023.01.13.524015. 2023.
Nosema ceranae is an emergent microsporidia parasite of the European honey bee (Apis mellifera), which causes serious nosemosis implicated in honeybee colony losses worldwide. N. ceranae is an obligate intracellular eukaryotic parasite that mainly invades the midgut of honeybees. ...
Dynamics of an impulsive reaction-diffusion mosquitoes model with multiple control measures
Tags: Aedes, Modeling, Population modification/replacement, Population suppression, WolbachiaY. Li, H. Zhao and K. Wang, Mathematical Biosciences and Engineering, 20:775-806. 2023.
It is well-known that mosquito control is one of the effective methods to reduce and prevent the transmission of mosquito-borne diseases. In this paper, we formulate a reaction-diffusion impulsive hybrid model incorporating Wolbachia, impulsively spraying of insecticides, spatial ...
Bypassing Mendel’s First Law: Transmission Ratio Distortion in Mammals
Tags: Other mammals, Transmission distortionG. Friocourt, A. Perrin, P. A. Saunders, E. Nikalayevich, C. Voisset, C. Coutton, G. Martinez and F. Morel, International Journal Molecular Sciences, 24. 2023.
Mendel's law of segregation states that the two alleles at a diploid locus should be transmitted equally to the progeny. A genetic segregation distortion, also referred to as transmission ratio distortion (TRD), is a statistically significant deviation from this rule. TRD has ...
Single-cell transcriptome sequencing reveals Wolbachia-mediated modification in early stages of Drosophila spermatogenesis
Tags: Cytoplasmic incompatibility, Fruit fly, WolbachiaW. Dou, B. Sun, Y. Miao, D. Huang and J. Xiao, Proceedings of the Royal Society B: Biological Sciences, 290:20221963. 2023.
Wolbachia are the most widely distributed intracellular bacteria, and their most common effect on host phenotype is cytoplasmic incompatibility (CI). A variety of models have been proposed to decipher the molecular mechanism of CI, among which the host modification (HM) model ...
Heterogeneous distribution of sex ratio distorters in natural populations of the isopod Armadillidium vulgare
Tags: Sex distorter, WolbachiaS. Durand, B. Lheraud, I. Giraud, N. Bech, F. Grandjean, T. Rigaud, J. Peccoud and R. Cordaux, Biology Letters, 19:20220457. 2023.
In the isopod Armadillidium vulgare, many females produce progenies with female-biased sex ratios, owing to two feminizing sex ratio distorters (SRD): Wolbachia endosymbionts and the f element. We investigated the distribution and population dynamics of these SRD and ...
Effects of gamma radiation on the vector competence of Aedes aegypti (diptera: Culicidae) to transmit Zika virus
Tags: Aedes, Sterile insect technique (SIT)E. B. da Silva, C. M. de Mendonça, D. R. D. Guedes, M. H. S. Paiva, J. d. A. Mendonça, E. S. F. Dias, S. G. L. Florêncio, A. Amaral, A. M. Netto, C. F. J. A. Lopes and M. A. V. de Melo-Santos, Acta Tropica, 239:106831. 2023.
One of the limitations of the Sterile Insect Technique (SIT), conventionally performed by ionizing radiation, regards separating males from females, which is not 100% effective. Some irradiated females may be released together with males in the field at SIT. The present study ...
Trust in science and scientists: Effects of social attitudes and motivations on views regarding climate change, vaccines and gene drive technology
Tags: Ethics, Gene drive, Oceania, Stakeholder engagementH. G. W. Dixson, A. F. Komugabe-Dixson, F. Medvecky, J. Balanovic, H. Thygesen and E. A. MacDonald, Journal of Trust Research, 2023.
Trust in science and scientists (TSS) is an increasingly important topic with respect to how science is applied within society. However, its role regarding specific issues may vary depending upon other psychosocial factors. In this study, we investigated how trust interacts with ...
Sterility of Aedes albopictus by X-ray Irradiation as an Alternative to γ-ray Irradiation for the Sterile Insect Technique
Tags: Aedes, Sterile insect technique (SIT)L.-M. Wang, N. Li, C.-P. Ren, Z.-Y. Peng, H.-Z. Lu, D. Li, X.-Y. Wu, Z.-X. Zhou, J.-Y. Deng, Z.-H. Zheng, R.-Q. Wang, Y.-N. Du, D.-Q. Wang and S.-Q. Deng, Pathogens, 12. 2023.
The mosquito Aedes albopictus can transmit various arboviral diseases, posing a severe threat to human health. As an environmentally friendly method, sterile insect technology (SIT) is considered an alternative to traditional methods such as chemical pesticides to control Ae. ...
Assessment of distant-site rescue elements for CRISPR toxin-antidote gene drives
Tags: CRISPR, Gene drive, Gene drive synthetic, Toxin-antidoteJ. Chen, X. Xu and J. Champer, bioRxiv, 2023.01.06.522951. 2023.
New types of gene drives promise to provide increased flexibility, offering many options for confined modification or suppression of target populations. Among the most promising are CRISPR toxin-antidote gene drives, which disrupt essential wild-type genes by targeting them with ...
The Possibilities of Gene Drives for Managing Populations and Controlling Diseases
Tags: CRISPR, Gene drive, Gene drive synthetic, Replicator/site directed nucleaseJ. Vijay Upadhye, U. N. Shah and B. Mudhol, Salud, Ciencia y Tecnologia, 3. 2023.
The technical limitations and the use of gene drives to address ecological problems by modifying all populations of wild species remain primarily speculative. Here, we examine the possibility that RNA-guided gene drives based on the CRISPR nuclease Cas9 could be used as an ...
Gene drive designs for efficient and localisable population suppression using Y-linked editors
Tags: Gene drive, Gene drive synthetic, Genetic biocontrol, Modeling, Population suppression, Sex distorter, Sterile insect technique (SIT)R. Geci, K. Willis and A. Burt, PLOS Genetics, 18:e1010550. 2022.
Author summary Some pest populations can be successfully controlled by the inundative release of sterile males, but this approach is not practicable when the target population is large or the species difficult to rear. Computer modelling has previously demonstrated that releasing ...
Survival-Larval Density Relationships in the Field and Their Implications for Control of Container-Dwelling Aedes Mosquitoes
Tags: Aedes, Incompatible insect technique, Sterile insect technique (SIT)K. G. Evans, Z. R. Neale, B. Holly, C. C. Canizela and S. A. Juliano, Insects, 14. 2022.
Population density can affect survival, growth, development time, and adult size and fecundity, which are collectively known as density-dependent effects. Container Aedes larvae often attain high densities in nature, and those densities may be reduced when larval control is ...
Mating Competitiveness of Irradiated Lobesia botrana (Lepidoptera: Tortricidae) in Male-Only and Both Sex Release Strategies under Laboratory Cage Conditions
Tags: Moths, Sterile insect technique (SIT)G. Saour, A. Hashem and I. Jassem, Insects, 14. 2022.
This laboratory study explored the concept of whether irradiated male-only releases are more or equally efficient as releases of both irradiated males and females in the context of using the sterile insect technique/inherited sterility (SIT/IS) for the management of the European ...

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