Scholarly Literature
This is an aggregation of scholarly literature from peer-reviewed journals, bioRxiv , medRxiv and arXiv preprint servers focused on natural and engineered selfish genetic elements and genetic biocontrol. New citations are added as they appear. This content is intended for anyone interested in the scholarly literature on gene drive and genetic biocontrol.
Effects of a blood-free mosquito diet on fitness and gonotrophic cycle parameters of laboratory reared Anopheles gambiae sensu stricto
Tags: Anopheles, Mosquito husbandry, MosquitoesMosi, F.A., Rutha, I., Velez, R. et al., Parasites and Vectors, 17. 2024.
The current rise of new innovative tools for mosquito control, such as the release of transgenic mosquitoes carrying a dominant lethal gene and Wolbachia-based strategies, necessitates a massive production of mosquitoes in the insectary. However, currently laboratory rearing ...
Culex-Transmitted Diseases: Mechanisms, Impact, and Future Control Strategies using Wolbachia
Tags: Arbovirus, Culex, Mosquitoes, WolbachiaMadhav, M.; Blasdell, K.R.; Trewin, B.; Paradkar, P.N.; López-Denman, A.J., Viruses, 16:1134. 2024.
Mosquitoes of the Culex genus are responsible for a large burden of zoonotic virus transmission globally. Collectively, they play a significant role in the transmission of medically significant diseases such as Japanese encephalitis virus and West Nile virus. Climate change, ...
Assessing CRISPR/Cas9 potential in SDG3 attainment: malaria elimination—regulatory and community engagement landscape
Tags: CRISPR, Gene drive, MalariaSnuzik, A., Malaria Journal, 23. 2024.
Elimination of malaria has become a United Nations member states target: Target 3.3 of the sustainable development goal no. 3 (SDG3). Despite the measures taken, the attainment of this goal is jeopardized by an alarming trend of increasing malaria case incidence. Globally, there ...
Programming tumor evolution with selection gene drives to proactively combat drug resistance
Tags: Synthetic biologyLeighow, S.M., Reynolds, J.A., Sokirniy, I. et al., Nature Biotechnology, 2024.
Most targeted anticancer therapies fail due to drug resistance evolution. Here we show that tumor evolution can be reproducibly redirected to engineer therapeutic opportunity, regardless of the exact ensemble of pre-existing genetic heterogeneity. We develop a selection gene ...
Revisiting Wolbachia detections: Old and new issues in Aedes aegypti mosquitoes and other insects
Tags: Aedes, WolbachiaPerran A. Ross, Ary A. Hoffmann, Ecology and Evolution, 14. 2024.
Wolbachia continue to be reported in species previously thought to lack them, particularly Aedes aegypti mosquitoes. The presence of Wolbachia in this arbovirus vector is considered important because releases of mosquitoes with transinfected Wolbachia are being used around the ...
Mark–Release–Recapture (MRR) of Sterile Male Aedes albopictus (Skuse) in Sri Lanka: Field Performance of Sterile Males and Estimation of the Wild Mosquito Population Density
Tags: Dengue, Sterile insect technique (SIT)Hapugoda, Menaka, Nilmini Silva Gunawardena, Tharaka Ranathunge, Jeremy Bouyer, Hamidou Maiga, Kankanige Karunathilake, Gayan Parakrama Withanage, Indika Weerasinghe, Bazoumana B. D. Sow, and Jeevanie Harishchandra, Insects, 15:466. 2024.
Dengue is an important mosquito-borne disease in Sri Lanka. The Sterile Insect Technique (SIT) is an environment-friendly and novel method that can suppress dengue vector mosquitoes in Sri Lanka. This study aimed to evaluate the field performance of sterile males and the density ...
No Such Thing as Containment? Gene Drives for Conservation and the (Im)possibility of an Island
Tags: Biodiversity/Conservation, Containment, Gene driveBoersma, K., Bovenkerk, B. and Ludwig, D., Philosophy and Technology, 37:75. 2024.
This article explores the use of islands as tools of geographical and intellectual containment - or what we call “islanding” - in the scientific and policy literature about gene drive technologies in conservation. In the first part of the article, we explore the narrative of ...
Escalation of genome defense capacity enables control of an expanding meiotic driver
Tags: Genetics, Transmission distortionPeiwei Chen, Katherine C. Pan, Eunice H. Park, Yicheng Luo, Yuh Chwen G. Lee, Alexei A. Aravin, bioRxiv, 2024.
From RNA interference to chromatin silencing, diverse genome defense pathways silence selfish genetic elements to safeguard genome integrity1,2. Despite their diversity, different defense pathways share a modular organization, where numerous specificity factors identify diverse ...
Modeling the Evolution of S. pombe Populations with Multiple Killer Meiotic Drivers
Tags: Gene driveJosé Fabricio López Hernández, Boris Y Rubinstein, Robert L Unckless, Sarah E Zanders, G3 Genes|Genomes|Genetics, 2024.
Meiotic drivers are selfish genetic loci that can be transmitted to more than half of the viable gametes produced by a heterozygote. This biased transmission gives meiotic drivers an evolutionary advantage that can allow them to spread over generations until all members of a ...
Exploration of the potential of a boosted sterile insect technique to control fruit flies in mango orchards
Tags: Biological control, Fruit fly, Sterile insect technique (SIT)Esther Gnilane Diouf, Thierry Brévault, Saliou Ndiaye, Cyril Piou, Pest Management Science, 2024.
An innovative version of the sterile insect technique (SIT) for pest control, called boosted SIT, relies on the use of sterile males coated with a biocide to control a target wild pest population of the same species. The objective of the present study was to assess the relevance ...
Eliminating malaria vectors with precision-guided sterile males
Tags: Malaria, Sterile insect technique (SIT)Reema A. Apte, Andrea L. Smidler, James J. Pai, et al, Applied Biological Sciences, 121. 2024.
Controlling the principal African malaria vector, the mosquito Anopheles gambiae, is considered essential to curtail malaria transmission. However, existing vector control technologies rely on insecticides, which are becoming increasingly ineffective. Sterile insect technique ...
Germline Cas9 promoters with improved performance for homing gene drive
Tags: CRISPR, Genetic engineeringDu, J., Chen, W., Jia, X. et al., Nature Communications, 15:4560. 2024.
Gene drive systems could be a viable strategy to prevent pathogen transmission or suppress vector populations by propagating drive alleles with super-Mendelian inheritance. CRISPR-based homing gene drives convert wild type alleles into drive alleles in heterozygotes with Cas9 and ...
Upscaling irradiation protocols of Aedes albopictus pupae within an SIT program in Reunion Island
Tags: Sterile insect technique (SIT)Marquereau, L., Yamada, H., Damiens, D. et al., Scientific Reports, 14. 2024.
The implementation of the sterile insect technique against Aedes albopictus relies on many parameters, in particular on the success of the sterilization of males to be released into the target area in overflooding numbers to mate with wild females. Achieving consistent sterility ...
Simulation-based economic evaluation of the Wolbachia method in Brazil: a cost-effective strategy for dengue control
Tags: Dengue, South/Central America, WolbachiaIvan Ricardo Zimmermann, Ricardo Ribeiro Alves Fernandes, Márcia Gisele Santos da Costa, et al, The Lancet Regional Health - Americas, 35. 2024.
Dengue virus (DENV) is an arbovirus transmitted by Aedes aegypti mosquitoes, which can cause severe conditions such as hemorrhagic fever and dengue shock syndrome. These conditions are associated with adverse social, clinical, and economic consequences in Brazil. Herein, the ...
Curing mosquitoes with genetic approaches for malaria control
Tags: Anopheles, Gene editing, Malaria, Population modification/replacementMary Kefi, Victor Cardoso-Jaime, Sally A. Saab, George Dimopoulos, Trends in Parasitology, 2024.
Malaria remains a persistent global public health challenge because of the limitations of current prevention tools. The use of transgenic mosquitoes incapable of transmitting malaria, in conjunction with existing methods, holds promise for achieving elimination of malaria and ...
Transformation of meiotic drive into hybrid sterility in Drosophila
Tags: Fruit fly, Genetic incompatibilities, Sex distorter, Transmission distortionJackson Bladen, Hyuck-Jin Nam, Nitin Phadnis, bioRxiv, 2024.
Hybrid male sterility is one of the fastest evolving intrinsic reproductive barriers between recently isolated populations. A leading explanation for the evolution of hybrid male sterility involves genomic conflicts with meiotic drivers in the male germline. There are, however, ...
A Y chromosome-linked genome editor for efficient population suppression in the malaria vector Anopheles gambiae
Tags: Anopheles, Malaria, Synthetic biology, Vector controlIgnacio Tolosana, Katie Willis, Austin Burt, Matthew Gribble, Tony Nolan, Andrea Crisanti, Federica Bernardini, bioRxiv, 2024.
Genetic control – the deliberate introduction of genetic traits to control a pest or vector population – offers a powerful tool to augment conventional mosquito control tools that have been successful in reducing malaria burden but that are compromised by a range of ...
A small-molecule approach to restore female sterility phenotype targeted by a homing suppression gene drive in the fruit pest Drosophila suzukii
Tags: Gene driveMa S, Ni X, Chen S, Qiao X, Xu X, Chen W, et al., PLoS Genetics, 2024.
CRISPR-based gene drives offer promising prospects for controlling disease-transmitting vectors and agricultural pests. A significant challenge for successful suppression-type drive is the rapid evolution of resistance alleles. One approach to mitigate the development of ...
Wolbachia symbionts control sex in a parasitoid wasp using a horizontally acquired gene
Tags: Other arthropods, Other Symbionts, Population genetics/dynamics, Population suppressionLi C, Li CQ, Chen ZB, Liu BQ, Sun X, Wei KH, Li CY, Luan JB., Current Biology, 2024.
Host reproduction can be manipulated by bacterial symbionts in various ways. Parthenogenesis induction is the most effective type of reproduction manipulation by symbionts for their transmission. Insect sex is determined by regulation of doublesex (dsx) splicing through ...
Wolbachia infection-responsive immune genes suppress Plasmodium falciparum infection in Anopheles stephensi
Tags: Gene editing, Malaria, Mosquitoes, WolbachiaVandana V, Dong S, Sheth T, Sun Q, Wen H, Maldonado A, et al., PLoS Pathogens, 20. 2024.
Wolbachia, a maternally transmitted symbiotic bacterium of insects, can suppress a variety of human pathogens in mosquitoes, including malaria-causing Plasmodium in the Anopheles vector. However, the mechanistic basis of Wolbachia-mediated Plasmodium suppression in mosquitoes is ...
Comparing the long-term persistence of different Wolbachia strains after the release of bacteria-carrying mosquitoes
Tags: Aedes, Population genetics/dynamics, WolbachiaJose L. Orozco-Gonzales, Antone dos Santos Benedito, Daiver Cardona-Salgado et al., Mathematical Biosciences, 372. 2024.
This paper proposes a bidimensional modeling framework for Wolbachia invasion, assuming imperfect maternal transmission, incomplete cytoplasmic incompatibility, and direct infection loss due to thermal stress. Our model adapts to various Wolbachia strains and retains all ...
A naturally isolated symbiotic bacterium suppresses flavivirus transmission by Aedes mosquitoes
Tags: Aedes, MosquitoesLiming Zhang et al., Science, 384. 2024.
Flavivirus diseases are increasing in incidence and prevalence owing to the urban proclivities of its Aedes mosquito vector species. Extirpation of mosquitoes is considered key for the control of several human diseases but often involves toxic chemicals that prompt mosquito ...
Economic optimization of Wolbachia-infected Aedes aegypti release to prevent dengue
Tags: Aedes, WolbachiaHollingsworth BD, Cho C, Vella M, Roh H, Sass J, Lloyd AL, Brown ZS., Pest Management Science, 2024.
Dengue virus, primarily transmitted by the Aedes aegypti mosquito, is a major public health concern affecting ≈3.83 billion people worldwide. Recent releases of Wolbachia-transinfected Ae. aegypti in several cities worldwide have shown that it can reduce dengue transmission. ...
Altering traits and fates of wild populations with Mendelian DNA sequence modifying Allele Sails
Tags: CRISPR, Modeling, Synthetic biologyMichelle L. Johnson, Bruce A. Hay, Maciej Maselko, Nature Communications, 15. 2024.
Population-scale genome editing can be used to alter the composition or fate of wild populations. One approach to achieving these aims utilizes a synthetic gene drive element—a multi-gene cassette—to bring about an increase in the frequency of an existing allele. However, the ...
Genetic and geographic population structure in the malaria vector, Anopheles farauti, provides a candidate system for pioneering confinable gene-drive releases
Tags: Gene drive, MosquitoesAmbrose, L., Allen, S.L., Iro’ofa, C. et al., Heredity, 2024.
Indoor insecticide applications are the primary tool for reducing malaria transmission in the Solomon Archipelago, a region where Anopheles farauti is the only common malaria vector. Due to the evolution of behavioural resistance in some An. farauti populations, these ...
The Perpetual Vector Mosquito Threat and Its Eco-Friendly Nemeses
Tags: Aedes, Arbovirus, Biological controlMiranda, L.S.; Rudd, S.R.; Mena, O.; Hudspeth, P.E.; Barboza-Corona, J.E.; Park, H.-W.; Bideshi, D.K., Biology, 13:182. 2024.
Aedes, Culex, and Anopheles mosquitoes are the most prolific arthropod vectors of viral and parasitic agents of debilitating and lethal diseases in humans and animals. Despite some success in integrated pest management programs to control vectors, mosquito-borne diseases, such as ...
Wolbachia Infection through Hybridization to Enhance an Incompatible Insect Technique-Based Suppression of Aedes albopictus in Eastern Spain
Tags: Arbovirus, Cytoplasmic incompatibility, Genetic biocontrol, Population suppression, WolbachiaCholvi M, Trelis M, Bueno-Marí R, Khoubbane M, Gil R, Marcilla A, Moretti R., Insects, 15. 2024.
Wolbachia bacteria occur naturally as symbionts of many insect species and are responsible for various phenomena that modify the hosts’ reproductive biology. Among them, cytoplasmic incompatibility (CI) refers to the sterility of eggs produced by crosses between infected males ...
Detection and quantification of natural Wolbachia in Aedes aegypti in Metropolitan Manila, Philippines using locally designed primers
Tags: Aedes, Arbovirus, WolbachiaReyes JIL, Suzuki T, Suzuki Y, Watanabe K., Frontiers in Cellular and Infection Microbiology, 2024.
The Philippines bears health and economic burden caused by high dengue cases annually. Presently, the Philippines still lack an effective and sustainable vector management. The use of Wolbachia, a maternally transmitted bacterium, that mitigate arbovirus transmission has been ...
Talking About Gene Drive in Uganda: The Need for Science Communication to Underpin Engagement
Tags: Africa, Gene drive, Mosquitoes, Stakeholder engagementHartley, S., Stelmach, A., Opesen, C., Openjuru, G. L., and Neema, S., Science Communication, 2024.
Uganda may host the world’s first field trials of gene drive mosquitoes for malaria control. Global North discourses pre-suppose African publics have access to information about gene drive and are ready to make decisions about its governance. We explore assumptions about the ...
Monitoring Aedes populations for arboviruses, Wolbachia, insecticide resistance and its mechanisms in various agroecosystems in Benin
Tags: Aedes, Gene editing, Resistance, Vector control, WolbachiaS. Ateutchia-Ngouanet, F. Nanfack-Minkeu, K. Mavridis, S. Wanji, M. Demanou, J. Vontas, R. Djouaka, Acta Tropica, 253. 2024.
The susceptibility of arbovirus vectors to insecticides and the microbiome of Aedes species are understudied in Benin.
Between the lab and the Wild: Establishing the Potential of Gene Drive Mosquitoes for Malaria Control
Tags: MosquitoesMäkelin, M., Science as Culture, 2024.
Malaria control has been one of the defining goals in global health.
Wolbachia strain wAlbB shows favourable characteristics for dengue control use in Aedes aegypti from Burkina Faso
Tags: Aedes, Africa, WolbachiaMaria Vittoria Mancini, Shivan M. Murdochy, Etienne Bilgo, Thomas H. Ant, Daniel Gingell, Edounou Jacques Gnambani, Anna-Bella Failloux, Abdoulaye Diabate, Steven P. Sinkins, Environmental Microbiology, 26. 2024.
Dengue represents an increasing public health burden worldwide.
Alpha-mannosidase-2 modulates arbovirus infection in a pathogen- and Wolbachia-specific manner in Aedes aegypti mosquitoes
Tags: Aedes, CRISPR, WolbachiaNadya Urakova, Renuka E. Joseph, Allyn Huntsinger, Vanessa M. Macias, Matthew J. Jones, Leah T. Sigle, Ming Li, Omar S. Akbari, Zhiyong Xi, Konstantinos Lymperopoulos, Richard T. Sayre, Elizabeth A. McGraw, Jason L. Rasgon, Insect Molecular Biology, 2024.
Multiple Wolbachia strains can block pathogen infection, replication and/or transmission in Aedes aegypti mosquitoes under both laboratory and field conditions.
Prophage proteins alter long noncoding RNA and DNA of developing sperm to induce a paternal-effect lethality
Tags: Cytoplasmic incompatibility, WolbachiaRupinder Kaur et al., Science, 383:1111-1117. 2024.
Many arthropods carry symbiotic bacteria. Some, including Wolbachia strains, have the capacity to cause male sterility.
Comparative analysis of Wolbachia maternal transmission and localization in host ovaries
Tags: Fruit fly, Other Symbionts, WolbachiaMichael T.J. Hague, Timothy B. Wheeler, Brandon S. Cooper, bioRxiv, 2024.
Scientism, trust, value alignment, views of nature, and U.S. public opinion about gene drive mosquitos
Tags: Gene drive, Stakeholder engagementEvans, J. H., & Schairer, C. E., Public Understanding of Science, 2024.
Gene drive could be a powerful tool for addressing problems of conservation, agriculture, and human health caused by insect and animal pests but is likely to be controversial as it involves the release of genetically modified organisms. This study examined the social determinants ...
Acceptability of emergent Aedes aegypti vector control methods in Ponce, Puerto Rico: A qualitative assessment
Tags: Aedes, Genetically modified mosquitoes, Vector control, WolbachiaPérez-Guerra CL, Rosado-Santiago C, Ramos SA, Marrero-Santos KM, González-Zeno G, Partridge SK, et al., PLoS Global Public Health, 2024.
Aedes aegypti control has been fraught with challenges in Puerto Rico. The government has implemented commonly used vector control methods, but arboviral epidemics still occur. It is necessary to explore new Ae. aegypti control methods. This study aimed to understand the ...
Efficacy of Wolbachia-based mosquito control: Predictions of a spatially discrete mathematical model
Tags: Aedes, Mosquitoes, WolbachiaDavid Dye, John W. Cain, PLoS One, 19. 2024.
Wolbachia is an endosymbiont bacterium present in many insect species. When Wolbachia-carrying male Aedes aegypti mosquitoes mate with non-carrier females, their embryos are not viable due to cytoplasmic incompatibility. This phenomenon has been exploited successfully for the ...
Aedes aegypti Controls Ae. aegypti: SIT and IIT—An Overview
Tags: Aedes, Mosquitoes, Vector control, WolbachiaRobert L. Aldridge; Seth Gibson; Kenneth J. Linthicum, Journal of the American Mosquito Control Association, 20:32-49. 2024.
The sterile insect technique (SIT) and the incompatible insect technique (IIT) are emerging and potentially revolutionary tools for controlling Aedes aegypti (L.), a prominent worldwide mosquito vector threat to humans that is notoriously difficult to reduce or eliminate in ...
DENV-1 Titer Impacts Viral Blocking in wMel Aedes aegypti with Brazilian Genetic Background
Tags: Aedes, Dengue, WolbachiaCorrêa-Antônio, Jessica, Mariana R. David, Dinair Couto-Lima, Gabriela Azambuja Garcia, Milan S. G. Keirsebelik, Rafael Maciel-de-Freitas, and Márcio Galvão Pavan., Viruses, 16. 2024.
Several countries have been using Wolbachia deployments to replace highly competent native Aedes aegypti populations with Wolbachia-carrying mosquitoes with lower susceptibility to arboviruses such as dengue, Zika, and chikungunya. In Rio de Janeiro, Wolbachia deployments started ...
Effectiveness evaluation of mosquito suppression strategies on dengue transmission under changing temperature and precipitation
Tags: Dengue, Field trials, Mosquitoes, Population suppressionKaihui Liu, Shuanghui Fang, Qiong Li, et al., Acta Tropica, 2024.
PSRs: Selfish chromosomes that manipulate reproductive development
Tags: Chromosomal drive, Cytoplasmic incompatibility, WolbachiaXinmi Zhang, Patrick M. Ferree, Seminars in Cell and Developmental Biology, 159-160:66-73. 2024.
B chromosomes are intriguing “selfish” genetic elements, many of which exhibit higher-than-Mendelian transmission. This perspective highlights a group of B chromosomes known as Paternal Sex Ratio chromosomes (PSRs), which are found in several insects with haplo-diploid ...
Un1Cas12f1 and Cas9 gene drive in HSV1: viruses that ‘infect’ viruses
Tags: CRISPR, Gene driveQiaorui Yao, Zhuangjie Lin, Keyuan Lai, Xianying Zeng, Guanxiong Lei, Tongwen Zhang, Hongsheng Dai, bioRxiv, 2024.
Synthetic CRISPR-Cas9 gene drive has been developed as a potential tool to control harmful species. However, Cas9 gene drive faces high resistance rate and mitigation strategies developed so far are difficult to implement. Furthermore, studying the resistance to gene drive is ...
CRISPR-mediated germline mutagenesis for genetic sterilization of Anopheles gambiae males
Tags: Anopheles, CRISPR, Genetic engineering, Malaria, Mosquitoes, Sterile insect technique (SIT)Smidler, A.L., Marrogi, E., Kauffman, J. et al., Scientific Reports, 14. 2024.
Rapid spread of insecticide resistance among anopheline mosquitoes threatens malaria elimination efforts, necessitating development of alternative vector control technologies. Sterile insect technique (SIT) has been successfully implemented in multiple insect pests to suppress ...
Efficacy of Wolbachia-mediated sterility to reduce the incidence of dengue: a synthetic control study in Singapore
Tags: Field trials, Incompatible insect technique, WolbachiaJue Tao Lim, Somya Bansal*, Chee Seng Chong*, Borame Dickens, Youming Ng, Lu Deng, Caleb Lee, Li Yun Tan, Grace Chain, Pei Ma, Shuzhen Sim, Cheong Huat Tan, Alex R Cook, Lee Ching Ng, The Lancet Microbe, 2024.
Our study comprised an at-risk population of 607 872 individuals living in intervention sites and 3 894 544 individuals living in control sites. Interventions demonstrated up to 77·28% (121/156, 95% CI 75·81–78·58) intervention efficacy despite incomplete coverage ...
Acetylcholine esterase of Drosophila melanogaster: a laboratory model to explore insecticide susceptibility gene drives
Tags: Fruit fly, Gene driveHernandes, N., Qi, X.M., Bhide, S., Brown, C., Camm, B.J., Baxter, S.W. and Robin, C., Pest Management Science, 2024.
One of the proposed applications of gene drives has been to revert pesticide resistant mutations back to the ancestral susceptible state. Insecticides that have become ineffective because of the rise of resistance could have reinvigorated utility and be used to suppress pest ...
Introduction of Aedes aegypti mosquitoes carrying wAlbB Wolbachia sharply decreases dengue incidence in disease hotspots
Tags: Aedes, Population modification/replacement, WolbachiaAA Hoffmann, NW Ahmad, WM Keong, CY Ling, NA Ahmad, N. Golding, N. Tierney, J. Jelip, PW Putit, N Mohktar, SS Sandhu, LS Ming, et al., iScience, 2024.
Partial replacement of resident Aedes aegypti mosquitoes with introduced mosquitoes carrying certain strains of inherited Wolbachia symbionts can result in transmission blocking of dengue and other viruses of public health importance. Wolbachia strain wAlbB is an effective ...
Genome editing in pests: basic science to applications
Tags: CRISPR, Gene editing, Genetic biocontrol, ResistanceChen, X., Palli, S.R., Journal of Pest Science, 2024.
Recent developments in sequencing technologies produced enormous data on gene sequences and the identity of genes in many pest insects and disease vectors. However, the function of many of these genes is unknown. Functional genomics studies to uncover gene function in pest ...
Deep orange gene editing triggers temperature-sensitive lethal phenotypes in Ceratitis capitata
Tags: Fruit fly, Sterile insect technique (SIT)Sollazzo, G., Nikolouli, K., Gouvi, G. et al., BMC Biotechnology, 24. 2024.
The Mediterranean fruit fly, Ceratitis capitata, is a significant agricultural pest managed through area-wide integrated pest management (AW-IPM) including a sterile insect technique (SIT) component. Male-only releases increase the efficiency and cost-effectiveness of SIT ...
Meiotic drive against chromosome fusions in butterfly hybrids
Tags: Transmission distortionJesper Boman, Christer Wiklund, Roger Vila, Niclas Backström, bioRxiv, 2024.
Species frequently differ in karyotype, but heterokaryotypic individuals may suffer from reduced fitness. Chromosomal rearrangements like fissions and fusions can thus serve as a mechanism for speciation between incipient lineages but their evolution poses a paradox. How does ...
