Reply to: “Enhancement of Aedes aegypti susceptibility to dengue by Wolbachia is not supported”
C. Souto-Maior, J. G. King, L. M. Sartori, R. Maciel-de-Freitas and M. G. M. Gomes,
Nature Communications,
11:6113.
2020.
We recently reanalysed previously published datasets (Souto-Maior et al.1 and Ferguson et al.2). Using mathematical and statistical models based on these data, we showed that Wolbachia strain wMel increases mean and variance of Aedes aegypti susceptibility to infection by dengue viruses3. Ant et al.4 claim that concerns with the data and broader analysis make our conclusions misleading. We herein respond to their comments by demonstrating the robustness of our results to different treatments of the data, and expand our arguments for replacing currently adopted methods by those introduced in our paper. More related to this: Enhancement of Aedes aegypti susceptibility to dengue by Wolbachia is not supported Wolbachia as a possible means of driving genes into populations Wolbachia and cytoplasmic incompatibility in mosquitoes The mosquito strategy that could eliminate dengue
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